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Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism.
Pieretti S, Haanstra JR, Mazet M, Perozzo R, Bergamini C, Prati F, Fato R, Lenaz G, Capranico G, Brun R, Bakker BM, Michels PA, Scapozza L, Bolognesi ML, Cavalli A. Pieretti S, et al. Among authors: bolognesi ml. PLoS Negl Trop Dis. 2013;7(1):e2012. doi: 10.1371/journal.pntd.0002012. Epub 2013 Jan 17. PLoS Negl Trop Dis. 2013. PMID: 23350008 Free PMC article.
[4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors.
Tumiatti V, Angeli P, Andrisano V, Bolognesi ML, Cavalli A, Marucci G, Minarini A, Recanatini M, Rosini M, Melchiorre C. Tumiatti V, et al. Among authors: bolognesi ml. Bioorg Med Chem. 2000 Apr;8(4):681-9. doi: 10.1016/s0968-0896(99)00309-0. Bioorg Med Chem. 2000. PMID: 10819156
Heterocyclic inhibitors of AChE acylation and peripheral sites.
Bolognesi ML, Andrisano V, Bartolini M, Cavalli A, Minarini A, Recanatini M, Rosini M, Tumiatti V, Melchiorre C. Bolognesi ML, et al. Farmaco. 2005 Jun-Jul;60(6-7):465-73. doi: 10.1016/j.farmac.2005.03.010. Farmaco. 2005. PMID: 15878569 Review.
A small molecule targeting the multifactorial nature of Alzheimer's disease.
Cavalli A, Bolognesi ML, Capsoni S, Andrisano V, Bartolini M, Margotti E, Cattaneo A, Recanatini M, Melchiorre C. Cavalli A, et al. Among authors: bolognesi ml. Angew Chem Int Ed Engl. 2007;46(20):3689-92. doi: 10.1002/anie.200700256. Angew Chem Int Ed Engl. 2007. PMID: 17397121 No abstract available.
190 results