Lenaz G - Search Results

1

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism.

Pieretti S, Haanstra JR, Mazet M, Perozzo R, Bergamini C, Prati F, Fato R, Lenaz G, Capranico G, Brun R, Bakker BM, Michels PA, Scapozza L, Bolognesi ML, Cavalli A. Pieretti S, et al. Among authors: lenaz g. PLoS Negl Trop Dis. 2013;7(1):e2012. doi: 10.1371/journal.pntd.0002012. Epub 2013 Jan 17. PLoS Negl Trop Dis. 2013. PMID: 23350008 Free PMC article.

2

Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.

Bolognesi ML, Banzi R, Bartolini M, Cavalli A, Tarozzi A, Andrisano V, Minarini A, Rosini M, Tumiatti V, Bergamini C, Fato R, Lenaz G, Hrelia P, Cattaneo A, Recanatini M, Melchiorre C. Bolognesi ML, et al. Among authors: lenaz g. J Med Chem. 2007 Oct 4;50(20):4882-97. doi: 10.1021/jm070559a. Epub 2007 Sep 13. J Med Chem. 2007. PMID: 17850125

3

Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues.

Fato R, Bergamini C, Leoni S, Lenaz G. Fato R, et al. Among authors: lenaz g. Biofactors. 2008;32(1-4):31-9. doi: 10.1002/biof.5520320105. Biofactors. 2008. PMID: 19096098

4

Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks.

Bolognesi ML, Cavalli A, Bergamini C, Fato R, Lenaz G, Rosini M, Bartolini M, Andrisano V, Melchiorre C. Bolognesi ML, et al. Among authors: lenaz g. J Med Chem. 2009 Dec 10;52(23):7883-6. doi: 10.1021/jm901123n. J Med Chem. 2009. PMID: 19813747

5

Generation of reactive oxygen species by mitochondrial complex I: implications in neurodegeneration.

Fato R, Bergamini C, Leoni S, Strocchi P, Lenaz G. Fato R, et al. Among authors: lenaz g. Neurochem Res. 2008 Dec;33(12):2487-501. doi: 10.1007/s11064-008-9747-0. Epub 2008 Jun 6. Neurochem Res. 2008. PMID: 18535905 Review.

6

Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.

Simoni E, Bergamini C, Fato R, Tarozzi A, Bains S, Motterlini R, Cavalli A, Bolognesi ML, Minarini A, Hrelia P, Lenaz G, Rosini M, Melchiorre C. Simoni E, et al. Among authors: lenaz g. J Med Chem. 2010 Oct 14;53(19):7264-8. doi: 10.1021/jm100637k. J Med Chem. 2010. PMID: 20831222

7

A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells.

Bergamini C, Moruzzi N, Sblendido A, Lenaz G, Fato R. Bergamini C, et al. Among authors: lenaz g. PLoS One. 2012;7(3):e33712. doi: 10.1371/journal.pone.0033712. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22432044 Free PMC article.

8

Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species.

Fato R, Bergamini C, Bortolus M, Maniero AL, Leoni S, Ohnishi T, Lenaz G. Fato R, et al. Among authors: lenaz g. Biochim Biophys Acta. 2009 May;1787(5):384-92. doi: 10.1016/j.bbabio.2008.11.003. Epub 2008 Nov 14. Biochim Biophys Acta. 2009. PMID: 19059197 Free PMC article.

9

Mitochondrial quinone reductases: complex I.

Lenaz G, Fato R, Baracca A, Genova ML. Lenaz G, et al. Methods Enzymol. 2004;382:3-20. doi: 10.1016/S0076-6879(04)82001-9. Methods Enzymol. 2004. PMID: 15047093 Review. No abstract available.

10

Mitochondrial Complex I: structural and functional aspects.

Lenaz G, Fato R, Genova ML, Bergamini C, Bianchi C, Biondi A. Lenaz G, et al. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1406-20. doi: 10.1016/j.bbabio.2006.05.007. Epub 2006 May 12. Biochim Biophys Acta. 2006. PMID: 16828051 Free article. Review.

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