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Page 1
Alternative Runx1 promoter usage in mouse developmental hematopoiesis.
Bee T, Liddiard K, Swiers G, Bickley SR, Vink CS, Jarratt A, Hughes JR, Medvinsky A, de Bruijn MF. Bee T, et al. Among authors: de bruijn mf. Blood Cells Mol Dis. 2009 Jul-Aug;43(1):35-42. doi: 10.1016/j.bcmd.2009.03.011. Epub 2009 May 21. Blood Cells Mol Dis. 2009. PMID: 19464215
Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.
Wilkinson AC, Kawata VK, Schütte J, Gao X, Antoniou S, Baumann C, Woodhouse S, Hannah R, Tanaka Y, Swiers G, Moignard V, Fisher J, Hidetoshi S, Tijssen MR, de Bruijn MF, Liu P, Göttgens B. Wilkinson AC, et al. Among authors: de bruijn mf. Development. 2014 Oct;141(20):4018-30. doi: 10.1242/dev.115709. Epub 2014 Sep 24. Development. 2014. PMID: 25252941 Free PMC article.
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.
Harman JR, Thorne R, Jamilly M, Tapia M, Crump NT, Rice S, Beveridge R, Morrissey E, de Bruijn MFTR, Roberts I, Roy A, Fulga TA, Milne TA. Harman JR, et al. Among authors: de bruijn mftr. Genome Res. 2021 Jul;31(7):1159-1173. doi: 10.1101/gr.268490.120. Epub 2021 Jun 4. Genome Res. 2021. PMID: 34088716 Free PMC article.
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva EM, Demian AS, Brown J, Barone C, Patelli A, Harman JR, Nicholls M, Conway SJ, Morrissey E, Jacobsen SEW, Sparrow DB, Harris AL, Enver T, de Bruijn MFTR. Azzoni E, et al. Among authors: de bruijn mftr. Cell Rep. 2021 Dec 14;37(11):110103. doi: 10.1016/j.celrep.2021.110103. Cell Rep. 2021. PMID: 34910918 Free PMC article.
Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development.
Owens DDG, Anselmi G, Oudelaar AM, Downes DJ, Cavallo A, Harman JR, Schwessinger R, Bucakci A, Greder L, de Ornellas S, Jeziorska D, Telenius J, Hughes JR, de Bruijn MFTR. Owens DDG, et al. Among authors: de bruijn mftr. Nat Commun. 2022 Feb 9;13(1):773. doi: 10.1038/s41467-022-28376-8. Nat Commun. 2022. PMID: 35140205 Free PMC article.
A developmental route to hematopoietic stem cells.
Wilkinson AC, de Bruijn MFTR. Wilkinson AC, et al. Among authors: de bruijn mftr. Nat Biotechnol. 2024 Sep 18. doi: 10.1038/s41587-024-02398-7. Online ahead of print. Nat Biotechnol. 2024. PMID: 39294395 No abstract available.
76 results