Prime SS - Search Results

1

Progression of genotype-specific oral cancer leads to senescence of cancer-associated fibroblasts and is mediated by oxidative stress and TGF-β.

Hassona Y, Cirillo N, Lim KP, Herman A, Mellone M, Thomas GJ, Pitiyage GN, Parkinson EK, Prime SS. Hassona Y, et al. Among authors: prime ss. Carcinogenesis. 2013 Jun;34(6):1286-95. doi: 10.1093/carcin/bgt035. Epub 2013 Jan 27. Carcinogenesis. 2013. PMID: 23358854

2

Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma.

Lim KP, Cirillo N, Hassona Y, Wei W, Thurlow JK, Cheong SC, Pitiyage G, Parkinson EK, Prime SS. Lim KP, et al. Among authors: prime ss. J Pathol. 2011 Mar;223(4):459-69. doi: 10.1002/path.2841. Epub 2011 Jan 17. J Pathol. 2011. PMID: 21294120

3

Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs -1 and -2) in fibroblasts are early indicators of oral sub-mucous fibrosis and ageing.

Pitiyage GN, Lim KP, Gemenitzidis E, Teh MT, Waseem A, Prime SS, Tilakaratne WM, Fortune F, Parkinson EK. Pitiyage GN, et al. Among authors: prime ss. J Oral Pathol Med. 2012 Jul;41(6):454-62. doi: 10.1111/j.1600-0714.2012.01129.x. Epub 2012 Mar 3. J Oral Pathol Med. 2012. PMID: 22385081

4

A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.

Melling GE, Flannery SE, Abidin SA, Clemmens H, Prajapati P, Hinsley EE, Hunt S, Catto JWF, Coletta RD, Mellone M, Thomas GJ, Parkinson EK, Prime SS, Paterson IC, Buttle DJ, Lambert DW. Melling GE, et al. Among authors: prime ss. Carcinogenesis. 2018 May 28;39(6):798-807. doi: 10.1093/carcin/bgy032. Carcinogenesis. 2018. PMID: 29506142 Free article.

5

Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion.

Hassona Y, Cirillo N, Heesom K, Parkinson EK, Prime SS. Hassona Y, et al. Among authors: prime ss. Br J Cancer. 2014 Sep 9;111(6):1230-7. doi: 10.1038/bjc.2014.438. Epub 2014 Aug 12. Br J Cancer. 2014. PMID: 25117810 Free PMC article.

6

Fibroblast activation and senescence in oral cancer.

Prime SS, Cirillo N, Hassona Y, Lambert DW, Paterson IC, Mellone M, Thomas GJ, James EN, Parkinson EK. Prime SS, et al. J Oral Pathol Med. 2017 Feb;46(2):82-88. doi: 10.1111/jop.12456. Epub 2016 May 30. J Oral Pathol Med. 2017. PMID: 27237745 Review.

7

Cancer-associated fibroblasts regulate keratinocyte cell-cell adhesion via TGF-β-dependent pathways in genotype-specific oral cancer.

Cirillo N, Hassona Y, Celentano A, Lim KP, Manchella S, Parkinson EK, Prime SS. Cirillo N, et al. Among authors: prime ss. Carcinogenesis. 2017 Jan;38(1):76-85. doi: 10.1093/carcin/bgw113. Epub 2016 Nov 1. Carcinogenesis. 2017. PMID: 27803052

8

Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases.

Pitiyage GN, Slijepcevic P, Gabrani A, Chianea YG, Lim KP, Prime SS, Tilakaratne WM, Fortune F, Parkinson EK. Pitiyage GN, et al. Among authors: prime ss. J Pathol. 2011 Apr;223(5):604-17. doi: 10.1002/path.2839. Epub 2011 Feb 21. J Pathol. 2011. PMID: 21341274

9

Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression.

Rehman A, Ali S, Lone MA, Atif M, Hassona Y, Prime SS, Pitiyage GN, James EL, Parkinson EK. Rehman A, et al. Among authors: prime ss. J Oral Pathol Med. 2016 May;45(5):365-72. doi: 10.1111/jop.12370. Epub 2015 Sep 28. J Oral Pathol Med. 2016. PMID: 26414019

10

Keratinocytes synthesize and activate cortisol.

Cirillo N, Prime SS. Cirillo N, et al. Among authors: prime ss. J Cell Biochem. 2011 Jun;112(6):1499-505. doi: 10.1002/jcb.23081. J Cell Biochem. 2011. PMID: 21344493

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