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811 results

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Page 1
Efficacy, safety, pharmacokinetics, and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: a phase II study.
Zhu AX, Ancukiewicz M, Supko JG, Sahani DV, Blaszkowsky LS, Meyerhardt JA, Abrams TA, McCleary NJ, Bhargava P, Muzikansky A, Sheehan S, Regan E, Vasudev E, Knowles M, Fuchs CS, Ryan DP, Jain RK, Duda DG. Zhu AX, et al. Among authors: knowles m. Clin Cancer Res. 2013 Mar 15;19(6):1557-66. doi: 10.1158/1078-0432.CCR-12-3041. Epub 2013 Jan 29. Clin Cancer Res. 2013. PMID: 23362324 Free PMC article. Clinical Trial.
A phase 2 and biomarker study of cabozantinib in patients with advanced cholangiocarcinoma.
Goyal L, Zheng H, Yurgelun MB, Abrams TA, Allen JN, Cleary JM, Knowles M, Regan E, Reardon A, Khachatryan A, Jain RK, Nardi V, Borger DR, Duda DG, Zhu AX. Goyal L, et al. Among authors: knowles m. Cancer. 2017 Jun 1;123(11):1979-1988. doi: 10.1002/cncr.30571. Epub 2017 Feb 13. Cancer. 2017. PMID: 28192597 Free PMC article. Clinical Trial.
A Phase II and Biomarker Study of Sorafenib Combined with Modified FOLFOX in Patients with Advanced Hepatocellular Carcinoma.
Goyal L, Zheng H, Abrams TA, Miksad R, Bullock AJ, Allen JN, Yurgelun MB, Clark JW, Kambadakone A, Muzikansky A, Knowles M, Galway A, Afflitto AJ, Dinicola CF, Regan E, Hato T, Mamessier E, Shigeta K, Jain RK, Duda DG, Zhu AX. Goyal L, et al. Among authors: knowles m. Clin Cancer Res. 2019 Jan 1;25(1):80-89. doi: 10.1158/1078-0432.CCR-18-0847. Epub 2018 Sep 6. Clin Cancer Res. 2019. PMID: 30190369 Free PMC article. Clinical Trial.
Long G4-rich enhancers target promoters via a G4 DNA-based mechanism.
DeMeis JD, Roberts JT, Delcher HA, Godang NL, Coley AB, Brown CL, Shaw MH, Naaz S, Dahal A, Alqudah SY, Nguyen KN, Nguyen AD, Paudel SS, Shell JE, Patil SS, Dang H, O'Neal WK, Knowles MR, Houserova D, Gillespie MN, Borchert GM. DeMeis JD, et al. Among authors: knowles mr. Nucleic Acids Res. 2024 Dec 10:gkae1180. doi: 10.1093/nar/gkae1180. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39658038
Therapies Used by Children With Primary Ciliary Dyskinesia: A Natural History Study.
Gardner RA, Ferkol TW, Davis SD, Rosenfeld M, Sagel SD, Dell SD, Milla CE, Li L, Lin FC, Sullivan KM, Zariwala MA, Knowles MR, Leigh MW; Genetic Disorders of Mucociliary Clearance Consortium. Gardner RA, et al. Among authors: knowles mr. Pediatr Pulmonol. 2024 Nov 22:e27412. doi: 10.1002/ppul.27412. Online ahead of print. Pediatr Pulmonol. 2024. PMID: 39575633
Comparison of Longitudinal Outcomes in Children with Primary Ciliary Dyskinesia and Cystic Fibrosis.
Kinghorn B, Rosenfeld M, Sullivan E, Onchiri FM, Brown MD, Szczesniak R, Ferkol TW, Sagel SD, Dell SD, Milla C, Shapiro AJ, Sullivan KM, Zariwala MA, Pittman JE, Knowles MR, Davis SD, Leigh MW. Kinghorn B, et al. Among authors: knowles mr. Ann Am Thorac Soc. 2024 Dec;21(12):1723-1732. doi: 10.1513/AnnalsATS.202311-1008OC. Ann Am Thorac Soc. 2024. PMID: 39383539
Promoter Deletion Leading to Allele Specific Expression in a Genetically Unsolved Case of Primary Ciliary Dyskinesia.
Beaman MM, Yin W, Smith AJ, Sears PR, Leigh MW, Ferkol TW, Kearney B, Olivier KN, Kimple AJ, Clarke S, Huggins E, Nading E, Jung SH, Iyengar AK, Zou X, Dang H, Barrera A, Majoros WH, Rehder CW, Reddy TE, Ostrowski LE, Allen AS, Knowles MR, Zariwala MA, Crawford GE. Beaman MM, et al. Among authors: knowles mr. Am J Med Genet A. 2024 Oct 4:e63880. doi: 10.1002/ajmg.a.63880. Online ahead of print. Am J Med Genet A. 2024. PMID: 39364610
Genetic modifiers of body mass index in individuals with cystic fibrosis.
Ling H, Raraigh KS, Pugh EW, Aksit MA, Zhang P, Pace RG, Faino AV, Bamshad MJ, Gibson RL, O'Neal W, Knowles MR, Blackman SM, Cutting GR; CF Genome Project. Ling H, et al. Among authors: knowles mr. Am J Hum Genet. 2024 Oct 3;111(10):2203-2218. doi: 10.1016/j.ajhg.2024.08.004. Epub 2024 Sep 10. Am J Hum Genet. 2024. PMID: 39260370
The clinical utility of sequencing the entirety of CFTR.
Sheridan MB, Aksit MA, Pagel K, Hetrick K, Shultz-Lutwyche H, Myers B, Buckingham KJ, Pace RG, Ling H, Pugh E, O'Neal WK, Bamshad MJ, Gibson RL, Knowles MR, Blackman SM, Cutting GR, Raraigh KS. Sheridan MB, et al. Among authors: knowles mr. J Cyst Fibros. 2024 Jul;23(4):707-715. doi: 10.1016/j.jcf.2024.04.018. Epub 2024 May 11. J Cyst Fibros. 2024. PMID: 38734509
811 results