Dimitrov DS - Search Results

1

A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to the cancer cell surface.

Tang Z, Feng M, Gao W, Phung Y, Chen W, Chaudhary A, St Croix B, Qian M, Dimitrov DS, Ho M. Tang Z, et al. Among authors: dimitrov ds. Mol Cancer Ther. 2013 Apr;12(4):416-26. doi: 10.1158/1535-7163.MCT-12-0731. Epub 2013 Jan 31. Mol Cancer Ther. 2013. PMID: 23371858 Free PMC article.

2

Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain.

Chen W, Zhu Z, Feng Y, Xiao X, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. J Mol Biol. 2008 Oct 10;382(3):779-89. doi: 10.1016/j.jmb.2008.07.054. Epub 2008 Jul 26. J Mol Biol. 2008. PMID: 18687338 Free PMC article.

3

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers.

Chen W, Zhu Z, Feng Y, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17121-6. doi: 10.1073/pnas.0805297105. Epub 2008 Oct 28. Proc Natl Acad Sci U S A. 2008. PMID: 18957538 Free PMC article.

4

Construction of a human antibody domain (VH) library.

Chen W, Zhu Z, Xiao X, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Methods Mol Biol. 2009;525:81-99, xiii. doi: 10.1007/978-1-59745-554-1_4. Methods Mol Biol. 2009. PMID: 19252835 Free PMC article.

5

Human monoclonal antibodies and engineered antibody domains as HIV-1 entry inhibitors.

Chen W, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Curr Opin HIV AIDS. 2009 Mar;4(2):112-7. doi: 10.1097/COH.0b013e328322f95e. Curr Opin HIV AIDS. 2009. PMID: 19339949 Free PMC article. Review.

6

A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity.

Feng Y, Xiao X, Zhu Z, Streaker E, Ho M, Pastan I, Dimitrov DS. Feng Y, et al. Among authors: dimitrov ds. Mol Cancer Ther. 2009 May;8(5):1113-8. doi: 10.1158/1535-7163.MCT-08-0945. Epub 2009 May 5. Mol Cancer Ther. 2009. PMID: 19417159 Free PMC article.

7

A large human domain antibody library combining heavy and light chain CDR3 diversity.

Chen W, Zhu Z, Feng Y, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Mol Immunol. 2010 Jan;47(4):912-21. doi: 10.1016/j.molimm.2009.09.039. Epub 2009 Nov 1. Mol Immunol. 2010. PMID: 19883941 Free PMC article.

8

Identification and characterization of fully human anti-CD22 monoclonal antibodies.

Xiao X, Ho M, Zhu Z, Pastan I, Dimitrov DS. Xiao X, et al. Among authors: dimitrov ds. MAbs. 2009 May-Jun;1(3):297-303. doi: 10.4161/mabs.1.3.8113. Epub 2009 May 5. MAbs. 2009. PMID: 20065646 Free PMC article.

9

Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates.

Chen W, Xiao X, Wang Y, Zhu Z, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. Antiviral Res. 2010 Oct;88(1):107-15. doi: 10.1016/j.antiviral.2010.08.004. Epub 2010 Aug 13. Antiviral Res. 2010. PMID: 20709110 Free PMC article.

10

Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens.

Chen W, Feng Y, Gong R, Zhu Z, Wang Y, Zhao Q, Dimitrov DS. Chen W, et al. Among authors: dimitrov ds. J Virol. 2011 Sep;85(18):9395-405. doi: 10.1128/JVI.05119-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715496 Free PMC article.

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