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2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes.
Maula T, Isaksson YJ, García-Linares S, Niinivehmas S, Pentikäinen OT, Kurita M, Yamaguchi S, Yamamoto T, Katsumura S, Gavilanes JG, Martínez-del-Pozo A, Slotte JP. Maula T, et al. Among authors: gavilanes jg. Biochim Biophys Acta. 2013 May;1828(5):1390-5. doi: 10.1016/j.bbamem.2013.01.018. Epub 2013 Jan 30. Biochim Biophys Acta. 2013. PMID: 23376330 Free article.
Differential Effect of Bilayer Thickness on Sticholysin Activity.
Palacios-Ortega J, García-Linares S, Rivera-de-Torre E, Gavilanes JG, Martínez-Del-Pozo Á, Slotte JP. Palacios-Ortega J, et al. Among authors: gavilanes jg. Langmuir. 2017 Oct 17;33(41):11018-11027. doi: 10.1021/acs.langmuir.7b01765. Epub 2017 Oct 4. Langmuir. 2017. PMID: 28933861
186 results