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Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: data from 12,676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803.
Sargent D, Shi Q, Yothers G, Van Cutsem E, Cassidy J, Saltz L, Wolmark N, Bot B, Grothey A, Buyse M, de Gramont A; Adjuvant Colon Cancer End-points (ACCENT) Group. Sargent D, et al. Eur J Cancer. 2011 May;47(7):990-6. doi: 10.1016/j.ejca.2010.12.015. Epub 2011 Jan 21. Eur J Cancer. 2011. PMID: 21257306 Free PMC article.
Impact of age and medical comorbidity on adjuvant treatment outcomes for stage III colon cancer: a pooled analysis of individual patient data from four randomized, controlled trials.
Haller DG, O'Connell MJ, Cartwright TH, Twelves CJ, McKenna EF, Sun W, Saif MW, Lee S, Yothers G, Schmoll HJ. Haller DG, et al. Ann Oncol. 2015 Apr;26(4):715-724. doi: 10.1093/annonc/mdv003. Epub 2015 Jan 16. Ann Oncol. 2015. PMID: 25595934 Free PMC article. Clinical Trial.
Rapid reporting and review of an increased incidence of a known adverse event.
Sargent DJ, Goldberg RM, Mahoney MR, Hillman DW, McKeough T, Hamilton SF, Darcy JM, Anderson VL, Krook JE, O'Connell MJ. Sargent DJ, et al. J Natl Cancer Inst. 2000 Jun 21;92(12):1011-3. doi: 10.1093/jnci/92.12.1011. J Natl Cancer Inst. 2000. PMID: 10861314 No abstract available.
Prospectively randomized North Central Cancer Treatment Group trial of intensive-course fluorouracil combined with the l-isomer of intravenous leucovorin, oral leucovorin, or intravenous leucovorin for the treatment of advanced colorectal cancer.
Goldberg RM, Hatfield AK, Kahn M, Sargent DJ, Knost JA, O'Connell MJ, Krook JE, Maillard JA, Wiesenfeld M, Schaefer PL, Tirona MT, Moertel CG. Goldberg RM, et al. J Clin Oncol. 1997 Nov;15(11):3320-9. doi: 10.1200/JCO.1997.15.11.3320. J Clin Oncol. 1997. PMID: 9363861 Clinical Trial.
538 results