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148,139 results

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Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).
Takeuchi CS, Kim BG, Blazey CM, Ma S, Johnson HW, Anand NK, Arcalas A, Baik TG, Buhr CA, Cannoy J, Epshteyn S, Joshi A, Lara K, Lee MS, Wang L, Leahy JW, Nuss JM, Aay N, Aoyama R, Foster P, Lee J, Lehoux I, Munagala N, Plonowski A, Rajan S, Woolfrey J, Yamaguchi K, Lamb P, Miller N. Takeuchi CS, et al. Among authors: lee ms, lee j. J Med Chem. 2013 Mar 28;56(6):2218-34. doi: 10.1021/jm3007933. Epub 2013 Mar 7. J Med Chem. 2013. PMID: 23394126
Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.
Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, DeFina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, Joshi A, Kennedy AR, Kim AI, Lara K, Lee J, Li J, Lougheed JC, Ma S, Malek S, Manalo JC, Martini JF, McGrath G, Nicoll M, Nuss JM, Pack M, Peto CJ, Tsang TH, Wang L, Womble SW, Yakes M, Zhang W, Rice KD. Bussenius J, et al. Among authors: lee j. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5396-404. doi: 10.1016/j.bmcl.2012.07.052. Epub 2012 Jul 21. Bioorg Med Chem Lett. 2012. PMID: 22877636
Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors.
Lackner MR, Kindt RM, Carroll PM, Brown K, Cancilla MR, Chen C, de Silva H, Franke Y, Guan B, Heuer T, Hung T, Keegan K, Lee JM, Manne V, O'Brien C, Parry D, Perez-Villar JJ, Reddy RK, Xiao H, Zhan H, Cockett M, Plowman G, Fitzgerald K, Costa M, Ross-Macdonald P. Lackner MR, et al. Among authors: lee jm. Cancer Cell. 2005 Apr;7(4):325-36. doi: 10.1016/j.ccr.2005.03.024. Cancer Cell. 2005. PMID: 15837622 Free article.
Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain.
Silberfeld A, Roe JM, Ellegood J, Lerch JP, Qiu L, Kim Y, Lee JG, Hopkins WD, Grandjean J, Ou Y, Pourquié O. Silberfeld A, et al. Among authors: lee jg. Neuroimage. 2025 Jan 9:121017. doi: 10.1016/j.neuroimage.2025.121017. Online ahead of print. Neuroimage. 2025. PMID: 39798830
Euglena gracilis-derived β-glucan ameliorates particulate matter (PM2.5)-induced airway inflammation by modulating nuclear factor kappa B, mitogen-activated protein kinase, and nuclear factor erythroid 2-related factor 2 signaling pathways in A549 cells and BALB/c mice.
You YL, Byun HJ, Chang Y, Kim H, Lee H, Suh HJ, Jeon JY, Kim BR, Hwang JE, Lee JH, Choi HS. You YL, et al. Among authors: lee jh. Int J Biol Macromol. 2025 Jan 9:139671. doi: 10.1016/j.ijbiomac.2025.139671. Online ahead of print. Int J Biol Macromol. 2025. PMID: 39798741
Late-gadolinium enhancement predicts appropriate device therapies in non-ischemic recipients of primary prevention implantable cardioverter-defibrillators.
Kiang A, Al-Deiri D, Wang TKM, Nezafat R, Rizkallah D, Callahan TD, Lee JZ, Santangeli P, Wazni OM, Varma N, Nguyen C, Sroubek J, Kwon D. Kiang A, et al. Among authors: lee jz. Heart Rhythm. 2025 Jan 9:S1547-5271(25)00010-4. doi: 10.1016/j.hrthm.2025.01.003. Online ahead of print. Heart Rhythm. 2025. PMID: 39798682
148,139 results
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