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First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies.
Weiss GJ, Chao J, Neidhart JD, Ramanathan RK, Bassett D, Neidhart JA, Choi CHJ, Chow W, Chung V, Forman SJ, Garmey E, Hwang J, Kalinoski DL, Koczywas M, Longmate J, Melton RJ, Morgan R, Oliver J, Peterkin JJ, Ryan JL, Schluep T, Synold TW, Twardowski P, Davis ME, Yen Y. Weiss GJ, et al. Among authors: hwang j. Invest New Drugs. 2013 Aug;31(4):986-1000. doi: 10.1007/s10637-012-9921-8. Epub 2013 Feb 9. Invest New Drugs. 2013. PMID: 23397498 Free PMC article. Clinical Trial.
Tumor Selective Silencing Using an RNAi-Conjugated Polymeric Nanopharmaceutical.
Svenson S, Case RI, Cole RO, Hwang J, Kabir SR, Lazarus D, Lim Soo P, Ng PS, Peters C, Shum P, Sweryda-Krawiec B, Tripathi S, van der Poll D, Eliasof S. Svenson S, et al. Among authors: hwang j. Mol Pharm. 2016 Mar 7;13(3):737-47. doi: 10.1021/acs.molpharmaceut.5b00608. Epub 2016 Feb 2. Mol Pharm. 2016. PMID: 26835715
Discovery of a Novel Cabazitaxel Nanoparticle-Drug Conjugate (CRLX522) with Improved Pharmacokinetic Properties and Anticancer Effects Using a β-Cyclodextrin-PEG Copolymer Based Delivery Platform.
Metcalf CA 3rd, Svenson S, Hwang J, Tripathi S, Gangal G, Kabir S, Lazarus D, Cole R, Sweryda-Krawiec B, Shum P, Brown D, Case RI, van der Poll D, Rohde E, Harlfinger S, Teng CH, Eliasof S. Metcalf CA 3rd, et al. Among authors: hwang j. J Med Chem. 2019 Nov 14;62(21):9541-9559. doi: 10.1021/acs.jmedchem.9b00892. Epub 2019 Oct 24. J Med Chem. 2019. PMID: 31593466
Hypothetical criteria and types for cochlear migraine.
Lai JT, Liu TC, Hwang JH. Lai JT, et al. Among authors: hwang jh. Medicine (Baltimore). 2025 Jan 10;104(2):e41127. doi: 10.1097/MD.0000000000041127. Medicine (Baltimore). 2025. PMID: 39792738
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