Edinger AL - Search Results

1

Nutrient transporters: the Achilles' heel of anabolism.

McCracken AN, Edinger AL. McCracken AN, et al. Among authors: edinger al. Trends Endocrinol Metab. 2013 Apr;24(4):200-8. doi: 10.1016/j.tem.2013.01.002. Epub 2013 Feb 8. Trends Endocrinol Metab. 2013. PMID: 23402769 Free PMC article. Review.

2

Controlling cell growth and survival through regulated nutrient transporter expression.

Edinger AL. Edinger AL. Biochem J. 2007 Aug 15;406(1):1-12. doi: 10.1042/BJ20070490. Biochem J. 2007. PMID: 17645414 Review.

3

Ceramide starves cells to death by downregulating nutrient transporter proteins.

Guenther GG, Peralta ER, Rosales KR, Wong SY, Siskind LJ, Edinger AL. Guenther GG, et al. Among authors: edinger al. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17402-7. doi: 10.1073/pnas.0802781105. Epub 2008 Nov 3. Proc Natl Acad Sci U S A. 2008. PMID: 18981422 Free PMC article.

4

Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression.

Edinger AL. Edinger AL. Biochem Soc Trans. 2009 Feb;37(Pt 1):253-8. doi: 10.1042/BST0370253. Biochem Soc Trans. 2009. PMID: 19143642 Review.

5

Ceramide-induced starvation triggers homeostatic autophagy.

Peralta ER, Edinger AL. Peralta ER, et al. Among authors: edinger al. Autophagy. 2009 Apr;5(3):407-9. doi: 10.4161/auto.5.3.7809. Epub 2009 Apr 9. Autophagy. 2009. PMID: 19202357

6

A new take on ceramide: starving cells by cutting off the nutrient supply.

Guenther GG, Edinger AL. Guenther GG, et al. Among authors: edinger al. Cell Cycle. 2009 Apr 15;8(8):1122-6. doi: 10.4161/cc.8.8.8161. Epub 2009 Apr 13. Cell Cycle. 2009. PMID: 19282666

7

Loss of TSC2 confers resistance to ceramide and nutrient deprivation.

Guenther GG, Liu G, Ramirez MU, McMonigle RJ, Kim SM, McCracken AN, Joo Y, Ushach I, Nguyen NL, Edinger AL. Guenther GG, et al. Among authors: edinger al. Oncogene. 2014 Apr 3;33(14):1776-87. doi: 10.1038/onc.2013.139. Epub 2013 Apr 22. Oncogene. 2014. PMID: 23604129 Free PMC article.

8

Design, Synthesis, and Anti-leukemic Activity of Stereochemically Defined Constrained Analogs of FTY720 (Gilenya).

Fransson R, McCracken AN, Chen B, McMonigle RJ, Edinger AL, Hanessian S. Fransson R, et al. Among authors: edinger al. ACS Med Chem Lett. 2013 Oct 10;4(10):969-73. doi: 10.1021/ml4002425. ACS Med Chem Lett. 2013. PMID: 24273632 Free PMC article.

9

Targeting cancer metabolism at the plasma membrane by limiting amino acid access through SLC6A14.

McCracken AN, Edinger AL. McCracken AN, et al. Among authors: edinger al. Biochem J. 2015 Sep 15;470(3):e17-9. doi: 10.1042/BJ20150721. Biochem J. 2015. PMID: 26341486 Free PMC article.

10

Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo.

Chen B, Roy SG, McMonigle RJ, Keebaugh A, McCracken AN, Selwan E, Fransson R, Fallegger D, Huwiler A, Kleinman MT, Edinger AL, Hanessian S. Chen B, et al. Among authors: edinger al. ACS Chem Biol. 2016 Feb 19;11(2):409-14. doi: 10.1021/acschembio.5b00761. Epub 2015 Dec 14. ACS Chem Biol. 2016. PMID: 26653336 Free PMC article.

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