Brown K - Search Results

1

Kinetic and mechanistic characterisation of Choline Kinase-α.

Hudson CS, Knegtel RM, Brown K, Charlton PA, Pollard JR. Hudson CS, et al. Among authors: brown k. Biochim Biophys Acta. 2013 Jun;1834(6):1107-16. doi: 10.1016/j.bbapap.2013.02.008. Epub 2013 Feb 13. Biochim Biophys Acta. 2013. PMID: 23416529

2

Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors.

Charrier JD, Miller A, Kay DP, Brenchley G, Twin HC, Collier PN, Ramaya S, Keily SB, Durrant SJ, Knegtel RM, Tanner AJ, Brown K, Curnock AP, Jimenez JM. Charrier JD, et al. Among authors: brown k. J Med Chem. 2011 Apr 14;54(7):2341-50. doi: 10.1021/jm101499u. Epub 2011 Mar 10. J Med Chem. 2011. PMID: 21391610

3

Crystal structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc substrate complex.

Brown K, Vial SC, Dedi N, Westcott J, Scally S, Bugg TD, Charlton PA, Cheetham GM. Brown K, et al. Protein Pept Lett. 2013 Sep;20(9):1002-8. doi: 10.2174/0929866511320090006. Protein Pept Lett. 2013. PMID: 22973843

4

Structural basis for the interaction of TAK1 kinase with its activating protein TAB1.

Brown K, Vial SC, Dedi N, Long JM, Dunster NJ, Cheetham GM. Brown K, et al. J Mol Biol. 2005 Dec 16;354(5):1013-20. doi: 10.1016/j.jmb.2005.09.098. Epub 2005 Nov 2. J Mol Biol. 2005. PMID: 16289117

5

Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors.

Brown K, Long JM, Vial SC, Dedi N, Dunster NJ, Renwick SB, Tanner AJ, Frantz JD, Fleming MA, Cheetham GM. Brown K, et al. J Biol Chem. 2004 Apr 30;279(18):18727-32. doi: 10.1074/jbc.M400031200. Epub 2004 Feb 6. J Biol Chem. 2004. PMID: 14766749 Free article.

6

Crystal structures and inhibitors of proteins involved in IL-2 release and T cell signaling.

Brown K, Cheetham GM. Brown K, et al. Vitam Horm. 2006;74:31-59. doi: 10.1016/S0083-6729(06)74002-X. Vitam Horm. 2006. PMID: 17027510 Review. No abstract available.

7

Coral histology reveals consistent declines in tissue integrity during a marine heatwave despite differences in bleaching severity.

Kruse E, Brown KT, Barott KL. Kruse E, et al. Among authors: brown kt. PeerJ. 2025 Jan 3;13:e18654. doi: 10.7717/peerj.18654. eCollection 2025. PeerJ. 2025. PMID: 39763704 Free PMC article.

8

Development and evaluation of a simulation-based early-mobility curriculum for paediatric intensive care nurses.

LaRosa JM, Lenker H, Azamfirei R, Morgenstern S, Hajnik K, Mennie C, Wieczorek B, Brown KM, Shilkofski N, Kudchadkar SR. LaRosa JM, et al. Among authors: brown km. Nurs Crit Care. 2025 Jan 6. doi: 10.1111/nicc.13215. Online ahead of print. Nurs Crit Care. 2025. PMID: 39763212

9

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries.

Lara-Castor L, O'Hearn M, Cudhea F, Miller V, Shi P, Zhang J, Sharib JR, Cash SB, Barquera S, Micha R, Mozaffarian D; Global Dietary Database. Lara-Castor L, et al. Nat Med. 2025 Jan 6. doi: 10.1038/s41591-024-03345-4. Online ahead of print. Nat Med. 2025. PMID: 39762424

10

Hospital antimicrobial stewardship funding and resourcing impact on broad-spectrum antibiotic use: a cross-sectional study.

Tu M, Shi ZH, Leung V, Brown KA, Schwartz KL, Daneman N, Langford BJ. Tu M, et al. Among authors: brown ka. Antimicrob Steward Healthc Epidemiol. 2024 Dec 26;4(1):e223. doi: 10.1017/ash.2024.461. eCollection 2024. Antimicrob Steward Healthc Epidemiol. 2024. PMID: 39758877 Free PMC article.

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