Cui Y - Search Results

1

Novel nanoparticles formulation for cassette dosing via intravenous injection in rats for high throughput pharmacokinetic screening and potential applications.

Chiang PC, Deng Y, Ubhayaka S, La H, Cui Y, Chou KJ, Ran Y, Wong H. Chiang PC, et al. Among authors: cui y. J Nanosci Nanotechnol. 2012 Oct;12(10):7993-8000. doi: 10.1166/jnn.2012.6653. J Nanosci Nanotechnol. 2012. PMID: 23421169

2

In vitro and in vivo evaluation of amorphous solid dispersions generated by different bench-scale processes, using griseofulvin as a model compound.

Chiang PC, Cui Y, Ran Y, Lubach J, Chou KJ, Bao L, Jia W, La H, Hau J, Sambrone A, Qin A, Deng Y, Wong H. Chiang PC, et al. Among authors: cui y. AAPS J. 2013 Apr;15(2):608-17. doi: 10.1208/s12248-013-9469-3. Epub 2013 Mar 2. AAPS J. 2013. PMID: 23456436 Free PMC article.

3

Systemic in vitro and in vivo evaluation for determining the feasibility of making an amorphous solid dispersion of a B-Raf (rapidly accelerated fibrosarcoma) inhibitor.

Cui Y, Chiang PC, Choo EF, Boggs J, Rudolph J, Grina J, Wenglowsky S, Ran Y. Cui Y, et al. Int J Pharm. 2013 Sep 15;454(1):241-8. doi: 10.1016/j.ijpharm.2013.06.064. Epub 2013 Jul 5. Int J Pharm. 2013. PMID: 23834830

4

Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the Hedgehog pathway inhibitor GDC-0449 in dogs: an investigation using preclinical studies and physiologically based pharmacokinetic modeling.

Wong H, Theil FP, Cui Y, Marsters JC Jr, Khojasteh SC, Vernillet L, La H, Song X, Wang H, Morinello EJ, Deng Y, Hop CE. Wong H, et al. Among authors: cui y. Drug Metab Dispos. 2010 Jul;38(7):1029-38. doi: 10.1124/dmd.110.032680. Epub 2010 Apr 20. Drug Metab Dispos. 2010. PMID: 20406853

5

Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3-dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery.

Chiang PC, Ran Y, Chou KJ, Cui Y, Wong H. Chiang PC, et al. Among authors: cui y. Nanoscale Res Lett. 2011 Jun 7;6(1):413. doi: 10.1186/1556-276X-6-413. Nanoscale Res Lett. 2011. PMID: 21711942 Free PMC article.

6

Evaluation of drug load and polymer by using a 96-well plate vacuum dry system for amorphous solid dispersion drug delivery.

Chiang PC, Ran Y, Chou KJ, Cui Y, Sambrone A, Chan C, Hart R. Chiang PC, et al. Among authors: cui y. AAPS PharmSciTech. 2012 Jun;13(2):713-22. doi: 10.1208/s12249-012-9795-2. Epub 2012 May 5. AAPS PharmSciTech. 2012. PMID: 22562615 Free PMC article.

7

Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide.

Cui Y, Xing C, Ran Y. Cui Y, et al. J Pharm Sci. 2010 Jul;99(7):3048-59. doi: 10.1002/jps.22077. J Pharm Sci. 2010. PMID: 20112429

8

GDC-0449-a potent inhibitor of the hedgehog pathway.

Robarge KD, Brunton SA, Castanedo GM, Cui Y, Dina MS, Goldsmith R, Gould SE, Guichert O, Gunzner JL, Halladay J, Jia W, Khojasteh C, Koehler MF, Kotkow K, La H, Lalonde RL, Lau K, Lee L, Marshall D, Marsters JC Jr, Murray LJ, Qian C, Rubin LL, Salphati L, Stanley MS, Stibbard JH, Sutherlin DP, Ubhayaker S, Wang S, Wong S, Xie M. Robarge KD, et al. Among authors: cui y. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5576-81. doi: 10.1016/j.bmcl.2009.08.049. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19716296

9

Applying nonexperimental study approach to analyze historical batch data.

Cui Y, Song X, Chuang K, Xie M. Cui Y, et al. J Pharm Sci. 2012 May;101(5):1865-76. doi: 10.1002/jps.23066. Epub 2012 Jan 30. J Pharm Sci. 2012. PMID: 22290332

10

Evaluation of hydrate-screening methods.

Cui Y, Yao E. Cui Y, et al. J Pharm Sci. 2008 Jul;97(7):2730-44. doi: 10.1002/jps.21187. J Pharm Sci. 2008. PMID: 17914731

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