Williams GM - Search Results

1

Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis.

Kueh JT, Choi KW, Williams GM, Moehle K, Bacsa B, Robinson JA, Brimble MA. Kueh JT, et al. Among authors: williams gm. Chemistry. 2013 Mar 18;19(12):3807-11. doi: 10.1002/chem.201204546. Epub 2013 Feb 19. Chemistry. 2013. PMID: 23424080

2

Synthesis of fish antifreeze neoglycopeptides using microwave-assisted "click chemistry".

Miller N, Williams GM, Brimble MA. Miller N, et al. Among authors: williams gm. Org Lett. 2009 Jun 4;11(11):2409-12. doi: 10.1021/ol9005536. Org Lett. 2009. PMID: 19473046

3

Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin.

Herbert KR, Williams GM, Cooper GJ, Brimble MA. Herbert KR, et al. Among authors: williams gm. Org Biomol Chem. 2012 Feb 14;10(6):1137-44. doi: 10.1039/c1ob06394d. Epub 2012 Jan 4. Org Biomol Chem. 2012. PMID: 22218394

4

Synthesis of a dicarba analogue of human β-defensin-1 using a combined ring closing metathesis--native chemical ligation strategy.

Heapy AM, Williams GM, Fraser JD, Brimble MA. Heapy AM, et al. Among authors: williams gm. Org Lett. 2012 Feb 3;14(3):878-81. doi: 10.1021/ol203407z. Epub 2012 Jan 12. Org Lett. 2012. PMID: 22239540

5

Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry.

Lee DJ, Yang SH, Williams GM, Brimble MA. Lee DJ, et al. Among authors: williams gm. J Org Chem. 2012 Sep 7;77(17):7564-71. doi: 10.1021/jo3013435. Epub 2012 Aug 17. J Org Chem. 2012. PMID: 22876975

6

Identification of key residues involved in adrenomedullin binding to the AM1 receptor.

Watkins HA, Au M, Bobby R, Archbold JK, Abdul-Manan N, Moore JM, Middleditch MJ, Williams GM, Brimble MA, Dingley AJ, Hay DL. Watkins HA, et al. Among authors: williams gm. Br J Pharmacol. 2013 May;169(1):143-55. doi: 10.1111/bph.12118. Br J Pharmacol. 2013. PMID: 23351143 Free PMC article.

7

Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds.

Williams GM, Cooper GJ, Lee K, Whiting L, Brimble MA. Williams GM, et al. Org Biomol Chem. 2013 May 21;11(19):3145-50. doi: 10.1039/c3ob40322j. Epub 2013 Mar 28. Org Biomol Chem. 2013. PMID: 23538787

8

Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates.

Wright TH, Brooks AE, Didsbury AJ, MacIntosh JD, Williams GM, Harris PW, Dunbar PR, Brimble MA. Wright TH, et al. Among authors: williams gm. Angew Chem Int Ed Engl. 2013 Sep 27;52(40):10616-9. doi: 10.1002/anie.201305620. Epub 2013 Aug 12. Angew Chem Int Ed Engl. 2013. PMID: 23939951

9

An important side reaction using the thiol, 3,6-dioxa-1,8-octanedithiol (DODT), in 9-fluorenylmethoxycarbonyl-based solid phase peptide synthesis.

Harris PW, Kowalczyk R, Yang SH, Williams GM, Brimble MA. Harris PW, et al. Among authors: williams gm. J Pept Sci. 2014 Mar;20(3):186-90. doi: 10.1002/psc.2595. Epub 2013 Dec 18. J Pept Sci. 2014. PMID: 24353069

10

Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin.

Lee KL, Middleditch MJ, Williams GM, Brimble MA, Cooper GJ. Lee KL, et al. Among authors: williams gm. Endocrinology. 2015 Mar;156(3):1194-9. doi: 10.1210/en.2014-1593. Epub 2014 Dec 29. Endocrinology. 2015. PMID: 25545381

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