Ramamoorthy A - Search Results

1

Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species.

Hyung SJ, DeToma AS, Brender JR, Lee S, Vivekanandan S, Kochi A, Choi JS, Ramamoorthy A, Ruotolo BT, Lim MH. Hyung SJ, et al. Among authors: ramamoorthy a. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3743-8. doi: 10.1073/pnas.1220326110. Epub 2013 Feb 20. Proc Natl Acad Sci U S A. 2013. PMID: 23426629 Free PMC article.

2

Orientation of amide-nitrogen-15 chemical shift tensors in peptides: a quantum chemical study.

Brender JR, Taylor DM, Ramamoorthy A. Brender JR, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2001 Feb 7;123(5):914-22. doi: 10.1021/ja001980q. J Am Chem Soc. 2001. PMID: 11456625

3

Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes.

Brender JR, Dürr UH, Heyl D, Budarapu MB, Ramamoorthy A. Brender JR, et al. Among authors: ramamoorthy a. Biochim Biophys Acta. 2007 Sep;1768(9):2026-9. doi: 10.1016/j.bbamem.2007.07.001. Epub 2007 Jul 12. Biochim Biophys Acta. 2007. PMID: 17662957 Free PMC article.

4

Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.

Brender JR, Lee EL, Cavitt MA, Gafni A, Steel DG, Ramamoorthy A. Brender JR, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2008 May 21;130(20):6424-9. doi: 10.1021/ja710484d. Epub 2008 Apr 30. J Am Chem Soc. 2008. PMID: 18444645 Free PMC article.

5

Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy.

Nanga RP, Brender JR, Xu J, Veglia G, Ramamoorthy A. Nanga RP, et al. Among authors: ramamoorthy a. Biochemistry. 2008 Dec 2;47(48):12689-97. doi: 10.1021/bi8014357. Biochemistry. 2008. PMID: 18989932 Free PMC article.

6

A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity.

Brender JR, Hartman K, Reid KR, Kennedy RT, Ramamoorthy A. Brender JR, et al. Among authors: ramamoorthy a. Biochemistry. 2008 Dec 2;47(48):12680-8. doi: 10.1021/bi801427c. Biochemistry. 2008. PMID: 18989933 Free PMC article.

7

Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin.

Barry J, Fritz M, Brender JR, Smith PE, Lee DK, Ramamoorthy A. Barry J, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2009 Apr 1;131(12):4490-8. doi: 10.1021/ja809217u. J Am Chem Soc. 2009. PMID: 19256547 Free PMC article.

8

Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide.

Smith PE, Brender JR, Ramamoorthy A. Smith PE, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2009 Apr 1;131(12):4470-8. doi: 10.1021/ja809002a. J Am Chem Soc. 2009. PMID: 19278224 Free PMC article.

9

Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy.

Soong R, Brender JR, Macdonald PM, Ramamoorthy A. Soong R, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2009 May 27;131(20):7079-85. doi: 10.1021/ja900285z. J Am Chem Soc. 2009. PMID: 19405534

10

Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.

Nanga RP, Brender JR, Xu J, Hartman K, Subramanian V, Ramamoorthy A. Nanga RP, et al. Among authors: ramamoorthy a. J Am Chem Soc. 2009 Jun 17;131(23):8252-61. doi: 10.1021/ja9010095. J Am Chem Soc. 2009. PMID: 19456151 Free PMC article.

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