Sahin-Tóth M - Search Results

1

Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation.

Batra J, Szabó A, Caulfield TR, Soares AS, Sahin-Tóth M, Radisky ES. Batra J, et al. J Biol Chem. 2013 Apr 5;288(14):9848-9859. doi: 10.1074/jbc.M113.457382. Epub 2013 Feb 19. J Biol Chem. 2013. PMID: 23430245 Free PMC article.

2

Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.

Sahin-Tóth M. Sahin-Tóth M. J Biol Chem. 1999 Oct 15;274(42):29699-704. doi: 10.1074/jbc.274.42.29699. J Biol Chem. 1999. PMID: 10514442 Free article.

3

Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.

Sahin-Tóth M. Sahin-Tóth M. J Biol Chem. 2000 Jul 28;275(30):22750-5. doi: 10.1074/jbc.M002943200. J Biol Chem. 2000. PMID: 10801865 Free article.

4

Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.

Kukor Z, Tóth M, Sahin-Tóth M. Kukor Z, et al. Eur J Biochem. 2003 May;270(9):2047-58. doi: 10.1046/j.1432-1033.2003.03581.x. Eur J Biochem. 2003. PMID: 12709065 Free article.

5

Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.

Szmola R, Kukor Z, Sahin-Tóth M. Szmola R, et al. J Biol Chem. 2003 Dec 5;278(49):48580-9. doi: 10.1074/jbc.M310301200. Epub 2003 Sep 24. J Biol Chem. 2003. PMID: 14507909 Free PMC article.

6

The tetra-aspartate motif in the activation peptide of human cationic trypsinogen is essential for autoactivation control but not for enteropeptidase recognition.

Nemoda Z, Sahin-Tóth M. Nemoda Z, et al. J Biol Chem. 2005 Aug 19;280(33):29645-52. doi: 10.1074/jbc.M505661200. Epub 2005 Jun 21. J Biol Chem. 2005. PMID: 15970597 Free PMC article.

7

Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen.

Nemoda Z, Sahin-Tóth M. Nemoda Z, et al. J Biol Chem. 2006 Apr 28;281(17):11879-86. doi: 10.1074/jbc.M600124200. Epub 2006 Feb 27. J Biol Chem. 2006. PMID: 16505482 Free PMC article.

8

Human mesotrypsin exhibits restricted S1' subsite specificity with a strong preference for small polar side chains.

Szepessy E, Sahin-Tóth M. Szepessy E, et al. FEBS J. 2006 Jul;273(13):2942-54. doi: 10.1111/j.1742-4658.2006.05305.x. Epub 2006 Jun 5. FEBS J. 2006. PMID: 16759229 Free PMC article.

9

Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y.

Szmola R, Sahin-Tóth M. Szmola R, et al. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11227-32. doi: 10.1073/pnas.0703714104. Epub 2007 Jun 25. Proc Natl Acad Sci U S A. 2007. PMID: 17592142 Free PMC article.

10

Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death.

Kereszturi E, Sahin-Tóth M. Kereszturi E, et al. J Biol Chem. 2009 Nov 27;284(48):33392-9. doi: 10.1074/jbc.M109.056812. Epub 2009 Sep 29. J Biol Chem. 2009. PMID: 19801634 Free PMC article.

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