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Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies.
Bhattacharyya S, Singh P, Rathore U, Purwar M, Wagner D, Arendt H, DeStefano J, LaBranche CC, Montefiori DC, Phogat S, Varadarajan R. Bhattacharyya S, et al. Among authors: varadarajan r. J Biol Chem. 2013 Apr 5;288(14):9815-9825. doi: 10.1074/jbc.M112.425959. Epub 2013 Feb 21. J Biol Chem. 2013. PMID: 23430741 Free PMC article.
Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: implications for targeting the CD4i epitope in human immunodeficiency virus vaccine design.
Varadarajan R, Sharma D, Chakraborty K, Patel M, Citron M, Sinha P, Yadav R, Rashid U, Kennedy S, Eckert D, Geleziunas R, Bramhill D, Schleif W, Liang X, Shiver J. Varadarajan R, et al. J Virol. 2005 Feb;79(3):1713-23. doi: 10.1128/JVI.79.3.1713-1723.2005. J Virol. 2005. PMID: 15650196 Free PMC article.
Protein minimization of the gp120 binding region of human CD4.
Sharma D, Balamurali MM, Chakraborty K, Kumaran S, Jeganathan S, Rashid U, Ingallinella P, Varadarajan R. Sharma D, et al. Among authors: varadarajan r. Biochemistry. 2005 Dec 13;44(49):16192-202. doi: 10.1021/bi051120s. Biochemistry. 2005. PMID: 16331979
216 results