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62 results

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Mutant HSP70 reverses autoimmune depigmentation in vitiligo.
Mosenson JA, Zloza A, Nieland JD, Garrett-Mayer E, Eby JM, Huelsmann EJ, Kumar P, Denman CJ, Lacek AT, Kohlhapp FJ, Alamiri A, Hughes T, Bines SD, Kaufman HL, Overbeck A, Mehrotra S, Hernandez C, Nishimura MI, Guevara-Patino JA, Le Poole IC. Mosenson JA, et al. Sci Transl Med. 2013 Feb 27;5(174):174ra28. doi: 10.1126/scitranslmed.3005127. Sci Transl Med. 2013. PMID: 23447019 Free PMC article.
HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo.
Denman CJ, McCracken J, Hariharan V, Klarquist J, Oyarbide-Valencia K, Guevara-Patiño JA, Le Poole IC. Denman CJ, et al. J Invest Dermatol. 2008 Aug;128(8):2041-8. doi: 10.1038/jid.2008.45. Epub 2008 Mar 13. J Invest Dermatol. 2008. PMID: 18337834 Free PMC article.
Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection.
Bellavance EC, Kohlhapp FJ, Zloza A, O'Sullivan JA, McCracken J, Jagoda MC, Lacek AT, Posner MC, Guevara-Patino JA. Bellavance EC, et al. J Immunol. 2011 Mar 15;186(6):3309-16. doi: 10.4049/jimmunol.1002549. Epub 2011 Feb 2. J Immunol. 2011. PMID: 21289306 Free PMC article.
Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression.
O'Sullivan JA, Zloza A, Kohlhapp FJ, Moore TV, Lacek AT, Dulin NO, Guevara-Patiño JA. O'Sullivan JA, et al. Cancer Immunol Immunother. 2011 Nov;60(11):1543-51. doi: 10.1007/s00262-011-1043-1. Epub 2011 Jun 17. Cancer Immunol Immunother. 2011. PMID: 21681376 Free PMC article.
HSP70i is a critical component of the immune response leading to vitiligo.
Mosenson JA, Zloza A, Klarquist J, Barfuss AJ, Guevara-Patino JA, Poole IC. Mosenson JA, et al. Pigment Cell Melanoma Res. 2012 Jan;25(1):88-98. doi: 10.1111/j.1755-148X.2011.00916.x. Epub 2011 Nov 14. Pigment Cell Melanoma Res. 2012. PMID: 21978301 Free PMC article.
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses.
Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polić B, Al-Harthi L, Sperling AI, Guevara-Patiño JA. Zloza A, et al. Nat Med. 2012 Feb 26;18(3):422-8. doi: 10.1038/nm.2683. Nat Med. 2012. PMID: 22366950 Free PMC article.
Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Kohlhapp FJ, Huelsmann EJ, Lacek AT, Schenkel JM, Lusciks J, Broucek JR, Goldufsky JW, Hughes T, Zayas JP, Dolubizno H, Sowell RT, Kühner R, Burd S, Kubasiak JC, Nabatiyan A, Marshall S, Bommareddy PK, Li S, Newman JH, Monken CE, Shafikhani SH, Marzo AL, Guevara-Patino JA, Lasfar A, Thomas PG, Lattime EC, Kaufman HL, Zloza A. Kohlhapp FJ, et al. Cell Rep. 2016 Oct 18;17(4):957-965. doi: 10.1016/j.celrep.2016.09.068. Cell Rep. 2016. PMID: 27760326 Free PMC article.
62 results