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Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea.
Jayasena CN, Nijher GM, Abbara A, Murphy KG, Lim A, Patel D, Mehta A, Todd C, Donaldson M, Trew GH, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: abbara a. Clin Pharmacol Ther. 2010 Dec;88(6):840-7. doi: 10.1038/clpt.2010.204. Epub 2010 Oct 27. Clin Pharmacol Ther. 2010. PMID: 20980998 Clinical Trial.
The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans.
Jayasena CN, Nijher GM, Comninos AN, Abbara A, Januszewki A, Vaal ML, Sriskandarajah L, Murphy KG, Farzad Z, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: abbara a. J Clin Endocrinol Metab. 2011 Dec;96(12):E1963-72. doi: 10.1210/jc.2011-1408. Epub 2011 Oct 5. J Clin Endocrinol Metab. 2011. PMID: 21976724 Free PMC article.
Twice-daily subcutaneous injection of kisspeptin-54 does not abolish menstrual cyclicity in healthy female volunteers.
Jayasena CN, Comninos AN, Nijher GM, Abbara A, De Silva A, Veldhuis JD, Ratnasabapathy R, Izzi-Engbeaya C, Lim A, Patel DA, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: abbara a. J Clin Endocrinol Metab. 2013 Nov;98(11):4464-74. doi: 10.1210/jc.2013-1069. Epub 2013 Sep 12. J Clin Endocrinol Metab. 2013. PMID: 24030945 Free PMC article. Clinical Trial.
Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54.
Jayasena CN, Abbara A, Veldhuis JD, Comninos AN, Ratnasabapathy R, De Silva A, Nijher GM, Ganiyu-Dada Z, Mehta A, Todd C, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: abbara a. J Clin Endocrinol Metab. 2014 Jun;99(6):E953-61. doi: 10.1210/jc.2013-1569. Epub 2014 Feb 11. J Clin Endocrinol Metab. 2014. PMID: 24517142 Free PMC article. Clinical Trial.
Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization.
Jayasena CN, Abbara A, Comninos AN, Nijher GM, Christopoulos G, Narayanaswamy S, Izzi-Engbeaya C, Sridharan M, Mason AJ, Warwick J, Ashby D, Ghatei MA, Bloom SR, Carby A, Trew GH, Dhillo WS. Jayasena CN, et al. Among authors: abbara a. J Clin Invest. 2014 Aug;124(8):3667-77. doi: 10.1172/JCI75730. Epub 2014 Jul 18. J Clin Invest. 2014. PMID: 25036713 Free PMC article. Clinical Trial.
231 results