Gu LQ - Search Results

1

New quinazoline derivatives for telomeric G-quadruplex DNA: effects of an added phenyl group on quadruplex binding ability.

He JH, Liu HY, Li Z, Tan JH, Ou TM, Huang SL, An LK, Li D, Gu LQ, Huang ZS. He JH, et al. Among authors: gu lq. Eur J Med Chem. 2013 May;63:1-13. doi: 10.1016/j.ejmech.2013.01.051. Epub 2013 Feb 9. Eur J Med Chem. 2013. PMID: 23454529

2

Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.

Zhou JL, Lu YJ, Ou TM, Zhou JM, Huang ZS, Zhu XF, Du CJ, Bu XZ, Ma L, Gu LQ, Li YM, Chan AS. Zhou JL, et al. Among authors: gu lq. J Med Chem. 2005 Nov 17;48(23):7315-21. doi: 10.1021/jm050041b. J Med Chem. 2005. PMID: 16279791

3

Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.

Ou TM, Lu YJ, Zhang C, Huang ZS, Wang XD, Tan JH, Chen Y, Ma DL, Wong KY, Tang JC, Chan AS, Gu LQ. Ou TM, et al. Among authors: gu lq. J Med Chem. 2007 Apr 5;50(7):1465-74. doi: 10.1021/jm0610088. Epub 2007 Mar 9. J Med Chem. 2007. PMID: 17346034

4

Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.

Tan JH, Lu YJ, Huang ZS, Gu LQ, Wu JY. Tan JH, et al. Among authors: gu lq. Eur J Med Chem. 2007 Sep;42(9):1169-75. doi: 10.1016/j.ejmech.2007.02.002. Epub 2007 Feb 25. Eur J Med Chem. 2007. PMID: 17408812

5

9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.

Zhang WJ, Ou TM, Lu YJ, Huang YY, Wu WB, Huang ZS, Zhou JL, Wong KY, Gu LQ. Zhang WJ, et al. Among authors: gu lq. Bioorg Med Chem. 2007 Aug 15;15(16):5493-501. doi: 10.1016/j.bmc.2007.05.050. Epub 2007 May 25. Bioorg Med Chem. 2007. PMID: 17574421

6

Oxoisoaporphine alkaloid derivatives: synthesis, DNA binding affinity and cytotoxicity.

Tang H, Wang XD, Wei YB, Huang SL, Huang ZS, Tan JH, An LK, Wu JY, Chan AS, Gu LQ. Tang H, et al. Among authors: gu lq. Eur J Med Chem. 2008 May;43(5):973-80. doi: 10.1016/j.ejmech.2007.07.004. Epub 2007 Jul 15. Eur J Med Chem. 2008. PMID: 17720282

7

Synthesis, cytotoxic activities and structure-activity relationships of topoisomerase I inhibitors: indolizinoquinoline-5,12-dione derivatives.

Cheng Y, An LK, Wu N, Wang XD, Bu XZ, Huang ZS, Gu LQ. Cheng Y, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Apr 15;16(8):4617-25. doi: 10.1016/j.bmc.2008.02.036. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18296054

8

Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.

Pan L, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS. Pan L, et al. Among authors: gu lq. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3790-3. doi: 10.1016/j.bmcl.2008.05.039. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18524585

9

9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.

Ma Y, Ou TM, Hou JQ, Lu YJ, Tan JH, Gu LQ, Huang ZS. Ma Y, et al. Among authors: gu lq. Bioorg Med Chem. 2008 Aug 15;16(16):7582-91. doi: 10.1016/j.bmc.2008.07.029. Epub 2008 Jul 18. Bioorg Med Chem. 2008. PMID: 18674916

10

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ. Lu YJ, et al. Among authors: gu lq. J Med Chem. 2008 Oct 23;51(20):6381-92. doi: 10.1021/jm800497p. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821749

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