Worthington J - Search Results

1

The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway.

Yakkundi A, McCallum L, O'Kane A, Dyer H, Worthington J, McKeen HD, McClements L, Elliott C, McCarthy HO, Hirst DG, Robson T. Yakkundi A, et al. Among authors: worthington j. PLoS One. 2013;8(2):e55075. doi: 10.1371/journal.pone.0055075. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457460 Free PMC article.

2

FKBPL and peptide derivatives: novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism.

Valentine A, O'Rourke M, Yakkundi A, Worthington J, Hookham M, Bicknell R, McCarthy HO, McClelland K, McCallum L, Dyer H, McKeen H, Waugh DJ, Roberts J, McGregor J, Cotton G, James I, Harrison T, Hirst DG, Robson T. Valentine A, et al. Among authors: worthington j. Clin Cancer Res. 2011 Mar 1;17(5):1044-56. doi: 10.1158/1078-0432.CCR-10-2241. Epub 2011 Mar 1. Clin Cancer Res. 2011. PMID: 21364036 Free PMC article.

3

Human osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer.

McCarthy HO, Coulter JA, Worthington J, Robson T, Hirst DG. McCarthy HO, et al. Among authors: worthington j. J Gene Med. 2007 Jun;9(6):511-20. doi: 10.1002/jgm.1045. J Gene Med. 2007. PMID: 17471586

4

Nitric oxide synthase gene therapy enhances the toxicity of cisplatin in cancer cells.

Adams C, McCarthy HO, Coulter JA, Worthington J, Murphy C, Robson T, Hirst DG. Adams C, et al. Among authors: worthington j. J Gene Med. 2009 Feb;11(2):160-8. doi: 10.1002/jgm.1280. J Gene Med. 2009. PMID: 19062185

5

Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer.

Coulter JA, Page NL, Worthington J, Robson T, Hirst DG, McCarthy HO. Coulter JA, et al. Among authors: worthington j. J Gene Med. 2010 Sep;12(9):755-65. doi: 10.1002/jgm.1495. J Gene Med. 2010. PMID: 20821746

6

The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation.

Coulter JA, McCarthy HO, Worthington J, Robson T, Scott S, Hirst DG. Coulter JA, et al. Among authors: worthington j. Gene Ther. 2008 Apr;15(7):495-503. doi: 10.1038/gt.2008.7. Epub 2008 Feb 7. Gene Ther. 2008. PMID: 18256696

7

Evaluation of the antiangiogenic potential of AQ4N.

O'Rourke M, Ward C, Worthington J, McKenna J, Valentine A, Robson T, Hirst DG, McKeown SR. O'Rourke M, et al. Among authors: worthington j. Clin Cancer Res. 2008 Mar 1;14(5):1502-9. doi: 10.1158/1078-0432.CCR-07-1262. Clin Cancer Res. 2008. PMID: 18316575 Free article.

8

Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype.

Butterworth KT, McCarthy HO, Devlin A, Ming L, Robson T, McKeown SR, Worthington J. Butterworth KT, et al. Among authors: worthington j. Int J Cancer. 2008 Aug 15;123(4):760-8. doi: 10.1002/ijc.23418. Int J Cancer. 2008. PMID: 18512241

9

p21((WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy.

McCarthy HO, Worthington J, Barrett E, Cosimo E, Boyd M, Mairs RJ, Ward C, McKeown SR, Hirst DG, Robson T. McCarthy HO, et al. Among authors: worthington j. Gene Ther. 2007 Feb;14(3):246-55. doi: 10.1038/sj.gt.3302871. Epub 2006 Sep 28. Gene Ther. 2007. PMID: 17006546

10

Radiogenic therapy: novel approaches for enhancing tumor radiosensitivity.

Robson T, Worthington J, McKeown SR, Hirst DG. Robson T, et al. Among authors: worthington j. Technol Cancer Res Treat. 2005 Aug;4(4):343-61. doi: 10.1177/153303460500400404. Technol Cancer Res Treat. 2005. PMID: 16029055 Free article. Review.

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