Xodo LE - Search Results

1

Guanidino anthrathiophenediones as G-quadruplex binders: uptake, intracellular localization, and anti-Harvey-Ras gene activity in bladder cancer cells.

Cogoi S, Shchekotikhin AE, Membrino A, Sinkevich YB, Xodo LE. Cogoi S, et al. Among authors: xodo le. J Med Chem. 2013 Apr 11;56(7):2764-78. doi: 10.1021/jm3019063. Epub 2013 Mar 21. J Med Chem. 2013. PMID: 23458775

2

RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.

Miglietta G, Cogoi S, Marinello J, Capranico G, Tikhomirov AS, Shchekotikhin A, Xodo LE. Miglietta G, et al. Among authors: xodo le. J Med Chem. 2017 Dec 14;60(23):9448-9461. doi: 10.1021/acs.jmedchem.7b00622. Epub 2017 Dec 1. J Med Chem. 2017. PMID: 29140695

3

Photodynamic Therapy for ras-Driven Cancers: Targeting G-Quadruplex RNA Structures with Bifunctional Alkyl-Modified Porphyrins.

Ferino A, Nicoletto G, D'Este F, Zorzet S, Lago S, Richter SN, Tikhomirov A, Shchekotikhin A, Xodo LE. Ferino A, et al. Among authors: xodo le. J Med Chem. 2020 Feb 13;63(3):1245-1260. doi: 10.1021/acs.jmedchem.9b01577. Epub 2020 Jan 24. J Med Chem. 2020. PMID: 31930916

4

Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells.

Cogoi S, Paramasivam M, Filichev V, Géci I, Pedersen EB, Xodo LE. Cogoi S, et al. Among authors: xodo le. J Med Chem. 2009 Jan 22;52(2):564-8. doi: 10.1021/jm800874t. J Med Chem. 2009. PMID: 19099510

5

G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.

Membrino A, Cogoi S, Pedersen EB, Xodo LE. Membrino A, et al. Among authors: xodo le. PLoS One. 2011;6(9):e24421. doi: 10.1371/journal.pone.0024421. Epub 2011 Sep 8. PLoS One. 2011. PMID: 21931711 Free PMC article.

6

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property.

Cogoi S, Shchekotikhin AE, Xodo LE. Cogoi S, et al. Among authors: xodo le. Nucleic Acids Res. 2014 Jul;42(13):8379-88. doi: 10.1093/nar/gku574. Epub 2014 Jul 10. Nucleic Acids Res. 2014. PMID: 25013182 Free PMC article.

7

Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells.

Cogoi S, Zorzet S, Shchekotikhin AE, Xodo LE. Cogoi S, et al. Among authors: xodo le. J Med Chem. 2015 Jul 23;58(14):5476-85. doi: 10.1021/acs.jmedchem.5b00409. Epub 2015 Jun 30. J Med Chem. 2015. PMID: 26057859 Free article.

8

Photosensitizers binding to nucleic acids as anticancer agents.

Xodo LE, Cogoi S, Rapozzi V. Xodo LE, et al. Future Med Chem. 2016;8(2):179-94. doi: 10.4155/fmc.15.180. Epub 2016 Jan 25. Future Med Chem. 2016. PMID: 26807879 Review.

9

Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.

Xodo L, Paramasivam M, Membrino A, Cogoi S. Xodo L, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):159-60. doi: 10.1093/nass/nrn081. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776302

10

Inhibition of gene expression by peptide nucleic acids in cultured cells.

Cogoi S, Rapozzi V, Xodo LE. Cogoi S, et al. Among authors: xodo le. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1615-8. doi: 10.1081/NCN-120023081. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565479

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