Lu D - Search Results

1

Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors.

Xing W, Fu Y, Shi Z, Lu D, Zhang H, Hu Y. Xing W, et al. Among authors: lu d. Eur J Med Chem. 2013 May;63:95-103. doi: 10.1016/j.ejmech.2013.01.056. Epub 2013 Feb 8. Eur J Med Chem. 2013. PMID: 23466605

2

Copper(I)-mediated cascade reactions: an efficient approach to the synthesis of functionalized benzofuro[3,2-d]pyrimidines.

Chao B, Lin S, Ma Q, Lu D, Hu Y. Chao B, et al. Among authors: lu d. Org Lett. 2012 May 4;14(9):2398-401. doi: 10.1021/ol300822a. Epub 2012 Apr 26. Org Lett. 2012. PMID: 22537017

3

Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis.

Xing W, Ai J, Jin S, Shi Z, Peng X, Wang L, Ji Y, Lu D, Liu Y, Geng M, Hu Y. Xing W, et al. Among authors: lu d. Eur J Med Chem. 2015 May 5;95:302-12. doi: 10.1016/j.ejmech.2015.03.041. Epub 2015 Mar 21. Eur J Med Chem. 2015. PMID: 25827399

4

A novel pyridazinone derivative inhibits hepatitis B virus replication by inducing genome-free capsid formation.

Wang YJ, Lu D, Xu YB, Xing WQ, Tong XK, Wang GF, Feng CL, He PL, Yang L, Tang W, Hu YH, Zuo JP. Wang YJ, et al. Among authors: lu d. Antimicrob Agents Chemother. 2015 Nov;59(11):7061-72. doi: 10.1128/AAC.01558-15. Epub 2015 Sep 8. Antimicrob Agents Chemother. 2015. PMID: 26349829 Free PMC article.

5

Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase.

Liu Y, Jin S, Peng X, Lu D, Zeng L, Sun Y, Ai J, Geng M, Hu Y. Liu Y, et al. Among authors: lu d. Eur J Med Chem. 2016 Jan 27;108:322-333. doi: 10.1016/j.ejmech.2015.11.042. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698536

6

Design and synthesis of novel benzo[d]oxazol-2(3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors.

Lu D, Shen A, Liu Y, Peng X, Xing W, Ai J, Geng M, Hu Y. Lu D, et al. Eur J Med Chem. 2016 Jun 10;115:191-200. doi: 10.1016/j.ejmech.2016.03.027. Epub 2016 Mar 12. Eur J Med Chem. 2016. PMID: 27017548

7

Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors.

Liu Y, Peng X, Guan X, Lu D, Xi Y, Jin S, Chen H, Zeng L, Ai J, Geng M, Hu Y. Liu Y, et al. Among authors: lu d. Eur J Med Chem. 2017 Jan 27;126:122-132. doi: 10.1016/j.ejmech.2016.10.003. Epub 2016 Oct 4. Eur J Med Chem. 2017. PMID: 27750146

8

Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation.

Lu D, Liu F, Xing W, Tong X, Wang L, Wang Y, Zeng L, Feng C, Yang L, Zuo J, Hu Y. Lu D, et al. ACS Infect Dis. 2017 Mar 10;3(3):199-205. doi: 10.1021/acsinfecdis.6b00159. Epub 2016 Dec 29. ACS Infect Dis. 2017. PMID: 27989113

9

Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives.

Lu D, Yan J, Wang L, Liu H, Zeng L, Zhang M, Duan W, Ji Y, Cao J, Geng M, Shen A, Hu Y. Lu D, et al. ACS Med Chem Lett. 2017 Jul 18;8(8):830-834. doi: 10.1021/acsmedchemlett.7b00172. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835797 Free PMC article.

10

Discovery and optimization of phthalazinone derivatives as a new class of potent dengue virus inhibitors.

Lu D, Liu J, Zhang Y, Liu F, Zeng L, Peng R, Yang L, Ying H, Tang W, Chen W, Zuo J, Tong X, Liu T, Hu Y. Lu D, et al. Eur J Med Chem. 2018 Feb 10;145:328-337. doi: 10.1016/j.ejmech.2018.01.008. Epub 2018 Jan 5. Eur J Med Chem. 2018. PMID: 29335200

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