Li Y - Search Results

1

Inhibition of LRP5/6-mediated Wnt/β-catenin signaling by Mesd attenuates hyperoxia-induced pulmonary hypertension in neonatal rats.

Alapati D, Rong M, Chen S, Lin C, Li Y, Wu S. Alapati D, et al. Among authors: li y. Pediatr Res. 2013 Jun;73(6):719-25. doi: 10.1038/pr.2013.42. Epub 2013 Mar 12. Pediatr Res. 2013. PMID: 23481549

2

The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.

Lin C, Lu W, Zhang W, Londoño-Joshi AI, Buchsbaum DJ, Bu G, Li Y. Lin C, et al. Among authors: li y. PLoS One. 2013;8(2):e58102. doi: 10.1371/journal.pone.0058102. Epub 2013 Feb 28. PLoS One. 2013. PMID: 23469146 Free PMC article.

3

Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells.

Lu W, Lin C, Li Y. Lu W, et al. Among authors: li y. Cell Signal. 2014 Jun;26(6):1303-9. doi: 10.1016/j.cellsig.2014.02.018. Epub 2014 Mar 6. Cell Signal. 2014. PMID: 24607787 Free PMC article.

4

Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo.

Lin C, Lu W, Zhai L, Bethea T, Berry K, Qu Z, Waud WR, Li Y. Lin C, et al. Among authors: li y. FEBS Lett. 2011 Oct 3;585(19):3120-5. doi: 10.1016/j.febslet.2011.08.046. Epub 2011 Sep 5. FEBS Lett. 2011. PMID: 21907199 Free PMC article.

5

Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells.

Lu W, Lin C, King TD, Chen H, Reynolds RC, Li Y. Lu W, et al. Among authors: li y. Cell Signal. 2012 Dec;24(12):2291-6. doi: 10.1016/j.cellsig.2012.07.009. Epub 2012 Jul 20. Cell Signal. 2012. PMID: 22820499 Free PMC article.

6

Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway.

Lu W, Lin C, Roberts MJ, Waud WR, Piazza GA, Li Y. Lu W, et al. Among authors: li y. PLoS One. 2011;6(12):e29290. doi: 10.1371/journal.pone.0029290. Epub 2011 Dec 16. PLoS One. 2011. PMID: 22195040 Free PMC article.

7

Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.

Li Y, Lu W, He X, Bu G. Li Y, et al. FEBS Lett. 2006 Oct 2;580(22):5423-8. doi: 10.1016/j.febslet.2006.09.011. Epub 2006 Sep 18. FEBS Lett. 2006. PMID: 16989816 Free article.

8

Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.

Li Y, Chen J, Lu W, McCormick LM, Wang J, Bu G. Li Y, et al. J Cell Sci. 2005 Nov 15;118(Pt 22):5305-14. doi: 10.1242/jcs.02651. Epub 2005 Nov 1. J Cell Sci. 2005. PMID: 16263759

9

LRP5/6 in Wnt signaling and tumorigenesis.

Li Y, Bu G. Li Y, et al. Future Oncol. 2005 Oct;1(5):673-81. doi: 10.2217/14796694.1.5.673. Future Oncol. 2005. PMID: 16556044 Review.

10

Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.

Lu W, Liu CC, Thottassery JV, Bu G, Li Y. Lu W, et al. Among authors: li y. Biochemistry. 2010 Jun 8;49(22):4635-43. doi: 10.1021/bi1001486. Biochemistry. 2010. PMID: 20446724 Free PMC article.

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