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Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.
Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy AN. Divakaruni AS, et al. Among authors: wiley se. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5422-7. doi: 10.1073/pnas.1303360110. Epub 2013 Mar 19. Proc Natl Acad Sci U S A. 2013. PMID: 23513224 Free PMC article.
Characterization of the human heart mitochondrial proteome.
Taylor SW, Fahy E, Zhang B, Glenn GM, Warnock DE, Wiley S, Murphy AN, Gaucher SP, Capaldi RA, Gibson BW, Ghosh SS. Taylor SW, et al. Nat Biotechnol. 2003 Mar;21(3):281-6. doi: 10.1038/nbt793. Epub 2003 Feb 18. Nat Biotechnol. 2003. PMID: 12592411
Excitotoxic injury to mitochondria isolated from cultured neurons.
Kushnareva YE, Wiley SE, Ward MW, Andreyev AY, Murphy AN. Kushnareva YE, et al. Among authors: wiley se. J Biol Chem. 2005 Aug 12;280(32):28894-902. doi: 10.1074/jbc.M503090200. Epub 2005 Jun 2. J Biol Chem. 2005. PMID: 15932874 Free article.
A conserved phosphatase cascade that regulates nuclear membrane biogenesis.
Kim Y, Gentry MS, Harris TE, Wiley SE, Lawrence JC Jr, Dixon JE. Kim Y, et al. Among authors: wiley se. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6596-601. doi: 10.1073/pnas.0702099104. Epub 2007 Apr 9. Proc Natl Acad Sci U S A. 2007. PMID: 17420445 Free PMC article.
Monitoring phosphorylation of the pyruvate dehydrogenase complex.
Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon JE. Rardin MJ, et al. Among authors: wiley se. Anal Biochem. 2009 Jun 15;389(2):157-64. doi: 10.1016/j.ab.2009.03.040. Epub 2009 Mar 31. Anal Biochem. 2009. PMID: 19341700 Free PMC article.
Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.
Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. Zhang J, et al. Among authors: wiley se. Cell Metab. 2011 Jun 8;13(6):690-700. doi: 10.1016/j.cmet.2011.04.007. Cell Metab. 2011. PMID: 21641550 Free PMC article.
44 results