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Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.
Morrow JP, Katchman A, Son NH, Trent CM, Khan R, Shiomi T, Huang H, Amin V, Lader JM, Vasquez C, Morley GE, D'Armiento J, Homma S, Goldberg IJ, Marx SO. Morrow JP, et al. Among authors: homma s. Circulation. 2011 Dec 20;124(25):2812-21. doi: 10.1161/CIRCULATIONAHA.111.056309. Epub 2011 Nov 28. Circulation. 2011. PMID: 22124376 Free PMC article.
Dietary Saturated Fat Promotes Arrhythmia by Activating NOX2 (NADPH Oxidase 2).
Joseph LC, Avula UMR, Wan EY, Reyes MV, Lakkadi KR, Subramanyam P, Nakanishi K, Homma S, Muchir A, Pajvani UB, Thorp EB, Reiken SR, Marks AR, Colecraft HM, Morrow JP. Joseph LC, et al. Among authors: homma s. Circ Arrhythm Electrophysiol. 2019 Nov;12(11):e007573. doi: 10.1161/CIRCEP.119.007573. Epub 2019 Oct 31. Circ Arrhythm Electrophysiol. 2019. PMID: 31665913 Free PMC article.
ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene.
Chatzifrangkeskou M, Le Dour C, Wu W, Morrow JP, Joseph LC, Beuvin M, Sera F, Homma S, Vignier N, Mougenot N, Bonne G, Lipson KE, Worman HJ, Muchir A. Chatzifrangkeskou M, et al. Among authors: homma s. Hum Mol Genet. 2016 Jun 1;25(11):2220-2233. doi: 10.1093/hmg/ddw090. Epub 2016 Apr 30. Hum Mol Genet. 2016. PMID: 27131347 Free PMC article.
Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J mice.
Hu C, Ge F, Hyodo E, Arai K, Iwata S, Lobdell H 4th, Walewski JL, Zhou S, Clugston RD, Jiang H, Zizola CP, Bharadwaj KG, Blaner WS, Homma S, Schulze PC, Goldberg IJ, Berk PD. Hu C, et al. Among authors: homma s. J Mol Cell Cardiol. 2013 Jun;59:30-40. doi: 10.1016/j.yjmcc.2013.02.005. Epub 2013 Feb 16. J Mol Cell Cardiol. 2013. PMID: 23422163 Free PMC article.
1,376 results