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ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice.
Tiveron C, Fasulo L, Capsoni S, Malerba F, Marinelli S, Paoletti F, Piccinin S, Scardigli R, Amato G, Brandi R, Capelli P, D'Aguanno S, Florenzano F, La Regina F, Lecci A, Manca A, Meli G, Pistillo L, Berretta N, Nisticò R, Pavone F, Cattaneo A. Tiveron C, et al. Among authors: meli g. Cell Death Differ. 2013 Aug;20(8):1017-30. doi: 10.1038/cdd.2013.22. Epub 2013 Mar 29. Cell Death Differ. 2013. PMID: 23538417 Free PMC article.
Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers.
Scopa C, Marrocco F, Latina V, Ruggeri F, Corvaglia V, La Regina F, Ammassari-Teule M, Middei S, Amadoro G, Meli G, Scardigli R, Cattaneo A. Scopa C, et al. Among authors: meli g. Cell Death Differ. 2020 Mar;27(3):934-948. doi: 10.1038/s41418-019-0409-3. Epub 2019 Oct 7. Cell Death Differ. 2020. PMID: 31591472 Free PMC article.
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.
Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D'Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G. Corsetti V, et al. Among authors: meli g. Hum Mol Genet. 2015 Jun 1;24(11):3058-81. doi: 10.1093/hmg/ddv059. Epub 2015 Feb 15. Hum Mol Genet. 2015. PMID: 25687137 Free article.
NGF steers microglia toward a neuroprotective phenotype.
Rizzi C, Tiberi A, Giustizieri M, Marrone MC, Gobbo F, Carucci NM, Meli G, Arisi I, D'Onofrio M, Marinelli S, Capsoni S, Cattaneo A. Rizzi C, et al. Among authors: meli g. Glia. 2018 Jul;66(7):1395-1416. doi: 10.1002/glia.23312. Epub 2018 Feb 23. Glia. 2018. PMID: 29473218 Free PMC article.
70 results