Drennan CL - Search Results

1

Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction.

Chang WC, Dey M, Liu P, Mansoorabadi SO, Moon SJ, Zhao ZK, Drennan CL, Liu HW. Chang WC, et al. Among authors: drennan cl. Nature. 2013 Apr 4;496(7443):114-8. doi: 10.1038/nature11998. Nature. 2013. PMID: 23552950 Free PMC article.

2

Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.

Higgins LJ, Yan F, Liu P, Liu HW, Drennan CL. Higgins LJ, et al. Among authors: drennan cl. Nature. 2005 Oct 6;437(7060):838-44. doi: 10.1038/nature03924. Epub 2005 Jul 13. Nature. 2005. PMID: 16015285

3

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.

Blasiak LC, Vaillancourt FH, Walsh CT, Drennan CL. Blasiak LC, et al. Among authors: drennan cl. Nature. 2006 Mar 16;440(7082):368-71. doi: 10.1038/nature04544. Nature. 2006. PMID: 16541079

4

Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.

Yun D, Dey M, Higgins LJ, Yan F, Liu HW, Drennan CL. Yun D, et al. Among authors: drennan cl. J Am Chem Soc. 2011 Jul 27;133(29):11262-9. doi: 10.1021/ja2025728. Epub 2011 Jun 30. J Am Chem Soc. 2011. PMID: 21682308 Free PMC article.

5

Visualizing molecular juggling within a B12-dependent methyltransferase complex.

Kung Y, Ando N, Doukov TI, Blasiak LC, Bender G, Seravalli J, Ragsdale SW, Drennan CL. Kung Y, et al. Among authors: drennan cl. Nature. 2012 Mar 14;484(7393):265-9. doi: 10.1038/nature10916. Nature. 2012. PMID: 22419154 Free PMC article.

6

Rheostat re-wired: alternative hypotheses for the control of thioredoxin reduction potentials.

Bewley KD, Dey M, Bjork RE, Mitra S, Chobot SE, Drennan CL, Elliott SJ. Bewley KD, et al. Among authors: drennan cl. PLoS One. 2015 Apr 13;10(4):e0122466. doi: 10.1371/journal.pone.0122466. eCollection 2015. PLoS One. 2015. PMID: 25874934 Free PMC article.

7

An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.

Bridwell-Rabb J, Kang G, Zhong A, Liu HW, Drennan CL. Bridwell-Rabb J, et al. Among authors: drennan cl. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13750-13755. doi: 10.1073/pnas.1613610113. Epub 2016 Nov 14. Proc Natl Acad Sci U S A. 2016. PMID: 27849620 Free PMC article.

8

A B₁₂-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.

Bridwell-Rabb J, Zhong A, Sun HG, Drennan CL, Liu HW. Bridwell-Rabb J, et al. Among authors: drennan cl. Nature. 2017 Apr 20;544(7650):322-326. doi: 10.1038/nature21689. Epub 2017 Mar 27. Nature. 2017. PMID: 28346939 Free PMC article.

9

The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.

Sintchak MD, Arjara G, Kellogg BA, Stubbe J, Drennan CL. Sintchak MD, et al. Among authors: drennan cl. Nat Struct Biol. 2002 Apr;9(4):293-300. doi: 10.1038/nsb774. Nat Struct Biol. 2002. PMID: 11875520

10

Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.

Dowling DP, Bruender NA, Young AP, McCarty RM, Bandarian V, Drennan CL. Dowling DP, et al. Among authors: drennan cl. Nat Chem Biol. 2014 Feb;10(2):106-12. doi: 10.1038/nchembio.1426. Epub 2013 Dec 22. Nat Chem Biol. 2014. PMID: 24362703 Free PMC article.

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