Jackson I - Search Results

1

Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet.

Stolarczyk E, Vong CT, Perucha E, Jackson I, Cawthorne MA, Wargent ET, Powell N, Canavan JB, Lord GM, Howard JK. Stolarczyk E, et al. Among authors: jackson i. Cell Metab. 2013 Apr 2;17(4):520-33. doi: 10.1016/j.cmet.2013.02.019. Cell Metab. 2013. PMID: 23562076 Free PMC article.

2

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

Powell N, Walker AW, Stolarczyk E, Canavan JB, Gökmen MR, Marks E, Jackson I, Hashim A, Curtis MA, Jenner RG, Howard JK, Parkhill J, MacDonald TT, Lord GM. Powell N, et al. Among authors: jackson i. Immunity. 2012 Oct 19;37(4):674-84. doi: 10.1016/j.immuni.2012.09.008. Epub 2012 Oct 11. Immunity. 2012. PMID: 23063332 Free PMC article.

3

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

Gökmen MR, Dong R, Kanhere A, Powell N, Perucha E, Jackson I, Howard JK, Hernandez-Fuentes M, Jenner RG, Lord GM. Gökmen MR, et al. Among authors: jackson i. J Immunol. 2013 Dec 15;191(12):5925-32. doi: 10.4049/jimmunol.1202254. Epub 2013 Nov 18. J Immunol. 2013. PMID: 24249732 Free PMC article.

4

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

Kanhere A, Hertweck A, Bhatia U, Gökmen MR, Perucha E, Jackson I, Lord GM, Jenner RG. Kanhere A, et al. Among authors: jackson i. Nat Commun. 2012;3:1268. doi: 10.1038/ncomms2260. Nat Commun. 2012. PMID: 23232398 Free PMC article.

5

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.

Hertweck A, Evans CM, Eskandarpour M, Lau JC, Oleinika K, Jackson I, Kelly A, Ambrose J, Adamson P, Cousins DJ, Lavender P, Calder VL, Lord GM, Jenner RG. Hertweck A, et al. Among authors: jackson i. Cell Rep. 2016 Jun 21;15(12):2756-70. doi: 10.1016/j.celrep.2016.05.054. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292648 Free PMC article.

6

A population of naive-like CD4⁺ T cells stably polarized to the T_H 1 lineage.

Lo JW, de Mucha MV, Henderson S, Roberts LB, Constable LE, Garrido-Mesa N, Hertweck A, Stolarczyk E, Houlder EL, Jackson I, MacDonald AS, Powell N, Neves JF, Howard JK, Jenner RG, Lord GM. Lo JW, et al. Among authors: jackson i. Eur J Immunol. 2022 Apr;52(4):566-581. doi: 10.1002/eji.202149228. Epub 2022 Feb 12. Eur J Immunol. 2022. PMID: 35092032 Free PMC article.

7

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes.

Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, Glimcher LH, Lord GM. Jenner RG, et al. Among authors: jackson i. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17876-81. doi: 10.1073/pnas.0909357106. Epub 2009 Oct 5. Proc Natl Acad Sci U S A. 2009. PMID: 19805038 Free PMC article.

8

microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance.

Anandagoda N, Willis JC, Hertweck A, Roberts LB, Jackson I, Gökmen MR, Jenner RG, Howard JK, Lord GM. Anandagoda N, et al. Among authors: jackson i. J Clin Invest. 2019 Mar 1;129(3):1257-1271. doi: 10.1172/JCI124725. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30741720 Free PMC article.

9

MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function.

Roberts LB, Jowett GM, Read E, Zabinski T, Berkachy R, Selkirk ME, Jackson I, Niazi U, Anandagoda N, Araki M, Araki K, Kasturiarachchi J, James C, Enver T, Nimmo R, Reis R, Howard JK, Neves JF, Lord GM. Roberts LB, et al. Among authors: jackson i. J Immunol. 2021 Jun 1;206(11):2725-2739. doi: 10.4049/jimmunol.2000647. Epub 2021 May 21. J Immunol. 2021. PMID: 34021046 Free PMC article.

10

Leptin-deficient mice are protected from accelerated nephrotoxic nephritis.

Tarzi RM, Cook HT, Jackson I, Pusey CD, Lord GM. Tarzi RM, et al. Among authors: jackson i. Am J Pathol. 2004 Feb;164(2):385-90. doi: 10.1016/S0002-9440(10)63128-8. Am J Pathol. 2004. PMID: 14742244 Free PMC article.

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