Aird KM - Search Results

1

Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Aird KM, et al. Cell Rep. 2013 Apr 25;3(4):1252-65. doi: 10.1016/j.celrep.2013.03.004. Epub 2013 Apr 4. Cell Rep. 2013. PMID: 23562156 Free PMC article.

2

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Tu Z, et al. Among authors: aird km. Dev Cell. 2011 Dec 13;21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. Dev Cell. 2011. PMID: 22137763 Free PMC article.

3

RAS, cellular senescence and transformation: the BRCA1 DNA repair pathway at the crossroads.

Tu Z, Aird KM, Zhang R. Tu Z, et al. Among authors: aird km. Small GTPases. 2012 Jul-Sep;3(3):163-7. doi: 10.4161/sgtp.19884. Epub 2012 Jul 1. Small GTPases. 2012. PMID: 22751483 Free PMC article.

4

Detection of senescence-associated heterochromatin foci (SAHF).

Aird KM, Zhang R. Aird KM, et al. Methods Mol Biol. 2013;965:185-96. doi: 10.1007/978-1-62703-239-1_12. Methods Mol Biol. 2013. PMID: 23296659 Free PMC article.

5

Chromatin remodeling, BRCA1, SAHF and cellular senescence.

Tu Z, Aird KM, Zhang R. Tu Z, et al. Among authors: aird km. Cell Cycle. 2013 Jun 1;12(11):1653-4. doi: 10.4161/cc.24986. Epub 2013 May 10. Cell Cycle. 2013. PMID: 23673322 Free PMC article. No abstract available.

6

Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer.

Aird KM, Li H, Xin F, Konstantinopoulos PA, Zhang R. Aird KM, et al. Cell Cycle. 2014;13(2):199-207. doi: 10.4161/cc.26953. Epub 2013 Oct 29. Cell Cycle. 2014. PMID: 24200970 Free PMC article.

7

Nucleotide metabolism, oncogene-induced senescence and cancer.

Aird KM, Zhang R. Aird KM, et al. Cancer Lett. 2015 Jan 28;356(2 Pt A):204-10. doi: 10.1016/j.canlet.2014.01.017. Epub 2014 Jan 29. Cancer Lett. 2015. PMID: 24486217 Free PMC article. Review.

8

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers.

Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Bitler BG, et al. Among authors: aird km. Nat Med. 2015 Mar;21(3):231-8. doi: 10.1038/nm.3799. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686104 Free PMC article.

9

ATM couples replication stress and metabolic reprogramming during cellular senescence.

Aird KM, Worth AJ, Snyder NW, Lee JV, Sivanand S, Liu Q, Blair IA, Wellen KE, Zhang R. Aird KM, et al. Cell Rep. 2015 May 12;11(6):893-901. doi: 10.1016/j.celrep.2015.04.014. Epub 2015 Apr 30. Cell Rep. 2015. PMID: 25937285 Free PMC article.

10

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.

Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. Caino MC, et al. Among authors: aird km. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124089 Free PMC article.

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