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New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation.
Chłoń-Rzepa G, Zmudzki P, Satała G, Duszyńska B, Partyka A, Wróbel D, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Pawłowski M, Zajdel P. Chłoń-Rzepa G, et al. Among authors: zmudzki p. Pharmacol Rep. 2013;65(1):15-29. doi: 10.1016/s1734-1140(13)70960-5. Pharmacol Rep. 2013. PMID: 23563020 Free article.
7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: zmudzki p. Bioorg Med Chem. 2007 Aug 1;15(15):5239-50. doi: 10.1016/j.bmc.2007.05.017. Epub 2007 May 10. Bioorg Med Chem. 2007. PMID: 17517514
Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
Rak A, Canale V, Marciniec K, Żmudzki P, Kotańska M, Knutelska J, Siwek A, Stachowicz G, Bednarski M, Nowiński L, Zygmunt M, Zajdel P, Sapa J. Rak A, et al. Among authors: zmudzki p. Bioorg Med Chem. 2016 Nov 1;24(21):5582-5591. doi: 10.1016/j.bmc.2016.09.017. Epub 2016 Sep 10. Bioorg Med Chem. 2016. PMID: 27658792
74 results