O'Hara JM - Search Results

1

Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen.

Thomas JC, O'Hara JM, Hu L, Gao FP, Joshi SB, Volkin DB, Brey RN, Fang J, Karanicolas J, Mantis NJ, Middaugh CR. Thomas JC, et al. Among authors: o hara jm. Hum Vaccin Immunother. 2013 Apr;9(4):744-52. doi: 10.4161/hv.22998. Epub 2013 Apr 1. Hum Vaccin Immunother. 2013. PMID: 23563512 Free PMC article.

2

Folding domains within the ricin toxin A subunit as targets of protective antibodies.

O'Hara JM, Neal LM, McCarthy EA, Kasten-Jolly JA, Brey RN 3rd, Mantis NJ. O'Hara JM, et al. Vaccine. 2010 Oct 8;28(43):7035-46. doi: 10.1016/j.vaccine.2010.08.020. Epub 2010 Aug 18. Vaccine. 2010. PMID: 20727394 Free PMC article.

3

Comparative efficacy of two leading candidate ricin toxin a subunit vaccines in mice.

O'Hara JM, Brey RN 3rd, Mantis NJ. O'Hara JM, et al. Clin Vaccine Immunol. 2013 Jun;20(6):789-94. doi: 10.1128/CVI.00098-13. Epub 2013 Mar 20. Clin Vaccine Immunol. 2013. PMID: 23515013 Free PMC article.

4

Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization.

Hassett KJ, Cousins MC, Rabia LA, Chadwick CM, O'Hara JM, Nandi P, Brey RN, Mantis NJ, Carpenter JF, Randolph TW. Hassett KJ, et al. Among authors: o hara jm. Eur J Pharm Biopharm. 2013 Oct;85(2):279-86. doi: 10.1016/j.ejpb.2013.03.029. Epub 2013 Apr 10. Eur J Pharm Biopharm. 2013. PMID: 23583494 Free PMC article.

5

LT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunity.

Greene CJ, Chadwick CM, Mandell LM, Hu JC, O'Hara JM, Brey RN 3rd, Mantis NJ, Connell TD. Greene CJ, et al. Among authors: o hara jm. PLoS One. 2013 Aug 2;8(8):e69678. doi: 10.1371/journal.pone.0069678. Print 2013. PLoS One. 2013. PMID: 23936344 Free PMC article.

6

Immunity to ricin: fundamental insights into toxin-antibody interactions.

O'Hara JM, Yermakova A, Mantis NJ. O'Hara JM, et al. Curr Top Microbiol Immunol. 2012;357:209-41. doi: 10.1007/82_2011_193. Curr Top Microbiol Immunol. 2012. PMID: 22113742 Free PMC article. Review.

7

Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.

O'Hara JM, Whaley K, Pauly M, Zeitlin L, Mantis NJ. O'Hara JM, et al. Vaccine. 2012 Feb 8;30(7):1239-43. doi: 10.1016/j.vaccine.2011.12.058. Epub 2011 Dec 22. Vaccine. 2012. PMID: 22197964 Free PMC article.

8

Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro.

O'Hara JM, Mantis NJ. O'Hara JM, et al. J Immunol Methods. 2013 Sep 30;395(1-2):71-8. doi: 10.1016/j.jim.2013.06.004. Epub 2013 Jun 15. J Immunol Methods. 2013. PMID: 23774033 Free PMC article.

9

Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA).

O'Hara JM, Kasten-Jolly JC, Reynolds CE, Mantis NJ. O'Hara JM, et al. Immunol Lett. 2014 Mar-Apr;158(1-2):7-13. doi: 10.1016/j.imlet.2013.11.009. Epub 2013 Nov 21. Immunol Lett. 2014. PMID: 24269767 Free PMC article.

10

A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.

Neal LM, O'Hara J, Brey RN 3rd, Mantis NJ. Neal LM, et al. Infect Immun. 2010 Jan;78(1):552-61. doi: 10.1128/IAI.00796-09. Epub 2009 Oct 26. Infect Immun. 2010. PMID: 19858297 Free PMC article.

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