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Rational design of a ligand-controlled protein conformational switch.
Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Dagliyan O, et al. Among authors: karginov av. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6800-4. doi: 10.1073/pnas.1218319110. Epub 2013 Apr 8. Proc Natl Acad Sci U S A. 2013. PMID: 23569285 Free PMC article.
Engineered allosteric activation of kinases in living cells.
Karginov AV, Ding F, Kota P, Dokholyan NV, Hahn KM. Karginov AV, et al. Nat Biotechnol. 2010 Jul;28(7):743-7. doi: 10.1038/nbt.1639. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581846 Free PMC article.
Engineering Pak1 Allosteric Switches.
Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Dagliyan O, et al. Among authors: karginov av. ACS Synth Biol. 2017 Jul 21;6(7):1257-1262. doi: 10.1021/acssynbio.6b00359. Epub 2017 Apr 6. ACS Synth Biol. 2017. PMID: 28365983 Free PMC article.
48 results