Geacintov NE - Search Results

1

Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not.

Kropachev K, Kolbanovskiy M, Liu Z, Cai Y, Zhang L, Schwaid AG, Kolbanovskiy A, Ding S, Amin S, Broyde S, Geacintov NE. Kropachev K, et al. Among authors: geacintov ne. Chem Res Toxicol. 2013 May 20;26(5):783-93. doi: 10.1021/tx400080k. Epub 2013 Apr 24. Chem Res Toxicol. 2013. PMID: 23570232 Free PMC article.

2

Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.

Krzeminski J, Kropachev K, Reeves D, Kolbanovskiy A, Kolbanovskiy M, Chen KM, Sharma AK, Geacintov N, Amin S, El-Bayoumy K. Krzeminski J, et al. Chem Res Toxicol. 2013 Nov 18;26(11):1746-54. doi: 10.1021/tx400296x. Epub 2013 Oct 30. Chem Res Toxicol. 2013. PMID: 24112095 Free PMC article.

3

Fluorescence characteristics of site-specific and stereochemically distinct benzo[a]pyrene diol epoxide-DNA adducts as probes of adduct conformation.

Huang W, Amin S, Geacintov NE. Huang W, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Feb;15(2):118-26. doi: 10.1021/tx010135y. Chem Res Toxicol. 2002. PMID: 11849037

4

Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.

Ruan Q, Kolbanovskiy A, Zhuang P, Chen J, Krzeminski J, Amin S, Geacintov NE. Ruan Q, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Feb;15(2):249-61. doi: 10.1021/tx010157k. Chem Res Toxicol. 2002. PMID: 11849052

5

Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.

Shafirovich V, Mock S, Kolbanovskiy A, Geacintov NE. Shafirovich V, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 Apr;15(4):591-7. doi: 10.1021/tx015593l. Chem Res Toxicol. 2002. PMID: 11952346

6

Conformational analysis of a 4-hydroxyequilenin Guanine adduct using density functional theory.

Yan S, Wu M, Ding S, Geacintov NE, Broyde S. Yan S, et al. Among authors: geacintov ne. Chem Res Toxicol. 2002 May;15(5):648-53. doi: 10.1021/tx0101797. Chem Res Toxicol. 2002. PMID: 12018985

7

Conformations of stereoisomeric base adducts to 4-hydroxyequilenin.

Ding S, Shapiro R, Geacintov NE, Broyde S. Ding S, et al. Among authors: geacintov ne. Chem Res Toxicol. 2003 Jun;16(6):695-707. doi: 10.1021/tx0340246. Chem Res Toxicol. 2003. PMID: 12807352

8

Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.

Wang L, Wu M, Yan SF, Patel DJ, Geacintov NE, Broyde S. Wang L, et al. Among authors: geacintov ne. Chem Res Toxicol. 2005 Mar;18(3):441-56. doi: 10.1021/tx049786v. Chem Res Toxicol. 2005. PMID: 15777084 Free PMC article.

9

Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics.

Ding S, Shapiro R, Geacintov NE, Broyde S. Ding S, et al. Among authors: geacintov ne. Biochemistry. 2005 Nov 8;44(44):14565-76. doi: 10.1021/bi051090t. Biochemistry. 2005. PMID: 16262256

10

Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin.

Kolbanovskiy A, Kuzmin V, Shastry A, Kolbanovskaya M, Chen D, Chang M, Bolton JL, Geacintov NE. Kolbanovskiy A, et al. Among authors: geacintov ne. Chem Res Toxicol. 2005 Nov;18(11):1737-47. doi: 10.1021/tx050190x. Chem Res Toxicol. 2005. PMID: 16300383

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