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Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.
Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, Gourdy P, Shaul PW, Henrion D, Arnal JF, Lenfant F. Adlanmerini M, et al. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E283-90. doi: 10.1073/pnas.1322057111. Epub 2013 Dec 26. Proc Natl Acad Sci U S A. 2014. PMID: 24371309 Free PMC article.
The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation.
Abot A, Fontaine C, Buscato M, Solinhac R, Flouriot G, Fabre A, Drougard A, Rajan S, Laine M, Milon A, Muller I, Henrion D, Adlanmerini M, Valéra MC, Gompel A, Gerard C, Péqueux C, Mestdagt M, Raymond-Letron I, Knauf C, Ferriere F, Valet P, Gourdy P, Katzenellenbogen BS, Katzenellenbogen JA, Lenfant F, Greene GL, Foidart JM, Arnal JF. Abot A, et al. EMBO Mol Med. 2014 Oct;6(10):1328-46. doi: 10.15252/emmm.201404112. EMBO Mol Med. 2014. PMID: 25214462 Free PMC article.
The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.
Smirnova NF, Fontaine C, Buscato M, Lupieri A, Vinel A, Valera MC, Guillaume M, Malet N, Foidart JM, Raymond-Letron I, Lenfant F, Gourdy P, Katzenellenbogen BS, Katzenellenbogen JA, Laffargue M, Arnal JF. Smirnova NF, et al. Circ Res. 2015 Oct 9;117(9):770-8. doi: 10.1161/CIRCRESAHA.115.306416. Epub 2015 Aug 27. Circ Res. 2015. PMID: 26316608 Free PMC article.
Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice.
Guillaume M, Riant E, Fabre A, Raymond-Letron I, Buscato M, Davezac M, Tramunt B, Montagner A, Smati S, Zahreddine R, Palierne G, Valera MC, Guillou H, Lenfant F, Unsicker K, Metivier R, Fontaine C, Arnal JF, Gourdy P. Guillaume M, et al. Hepatol Commun. 2019 Apr 29;3(7):908-924. doi: 10.1002/hep4.1363. eCollection 2019 Jul. Hepatol Commun. 2019. PMID: 31304450 Free PMC article.
65 results