Akutsu M - Search Results

1

Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.

Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, Furukawa Y. Kikuchi J, et al. Among authors: akutsu m. PLoS One. 2013 Apr 11;8(4):e60649. doi: 10.1371/journal.pone.0060649. Print 2013. PLoS One. 2013. PMID: 23593271 Free PMC article.

2

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.

Kikuchi J, Wada T, Shimizu R, Izumi T, Akutsu M, Mitsunaga K, Noborio-Hatano K, Nobuyoshi M, Ozawa K, Kano Y, Furukawa Y. Kikuchi J, et al. Among authors: akutsu m. Blood. 2010 Jul 22;116(3):406-17. doi: 10.1182/blood-2009-07-235663. Epub 2010 Mar 29. Blood. 2010. PMID: 20351311 Free article.

3

The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.

Kikuchi J, Yamada S, Koyama D, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Furukawa Y. Kikuchi J, et al. Among authors: akutsu m. J Biol Chem. 2013 Aug 30;288(35):25593-25602. doi: 10.1074/jbc.M113.480574. Epub 2013 Jul 22. J Biol Chem. 2013. PMID: 23878197 Free PMC article. Clinical Trial.

4

Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies.

Hiraoka N, Kikuchi J, Yamauchi T, Koyama D, Wada T, Uesawa M, Akutsu M, Mori S, Nakamura Y, Ueda T, Kano Y, Furukawa Y. Hiraoka N, et al. Among authors: akutsu m. PLoS One. 2014 Mar 13;9(3):e90675. doi: 10.1371/journal.pone.0090675. eCollection 2014. PLoS One. 2014. PMID: 24626203 Free PMC article.

5

Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.

Akutsu M, Furukawa Y, Tsunoda S, Izumi T, Ohmine K, Kano Y. Akutsu M, et al. Leukemia. 2002 Sep;16(9):1808-17. doi: 10.1038/sj.leu.2402573. Leukemia. 2002. PMID: 12200697

6

Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.

Kano Y, Akutsu M, Tsunoda S, Izumi T, Kobayashi H, Mano H, Furukawa Y. Kano Y, et al. Among authors: akutsu m. Invest New Drugs. 2007 Feb;25(1):31-40. doi: 10.1007/s10637-006-9000-0. Invest New Drugs. 2007. PMID: 16865529

7

The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.

Tanaka M, Kano Y, Akutsu M, Tsunoda S, Izumi T, Yazawa Y, Miyawaki S, Mano H, Furukawa Y. Tanaka M, et al. Among authors: akutsu m. Anticancer Res. 2009 Nov;29(11):4589-96. Anticancer Res. 2009. PMID: 20032408 Free article.

8

[Anti-parietal cell antibody].

Kano Y, Akutsu M. Kano Y, et al. Among authors: akutsu m. Nihon Rinsho. 2010 Jun;68 Suppl 6:602-4. Nihon Rinsho. 2010. PMID: 20942141 Japanese. No abstract available.

9

Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

Furukawa Y, Vu HA, Akutsu M, Odgerel T, Izumi T, Tsunoda S, Matsuo Y, Kirito K, Sato Y, Mano H, Kano Y. Furukawa Y, et al. Among authors: akutsu m. Leukemia. 2007 May;21(5):1005-14. doi: 10.1038/sj.leu.2404593. Epub 2007 Mar 1. Leukemia. 2007. PMID: 17330105

10

[Immunologic tests: Intrinsic factor antibody].

Kano Y, Akutsu M. Kano Y, et al. Among authors: akutsu m. Nihon Rinsho. 2005 Jul;63 Suppl 7:559-61. Nihon Rinsho. 2005. PMID: 16111331 Review. Japanese. No abstract available.

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