Izumi T - Search Results

1

Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.

Kikuchi J, Shibayama N, Yamada S, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Sugiyama K, Ohki M, Park SY, Furukawa Y. Kikuchi J, et al. Among authors: izumi t. PLoS One. 2013 Apr 11;8(4):e60649. doi: 10.1371/journal.pone.0060649. Print 2013. PLoS One. 2013. PMID: 23593271 Free PMC article.

2

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.

Kikuchi J, Wada T, Shimizu R, Izumi T, Akutsu M, Mitsunaga K, Noborio-Hatano K, Nobuyoshi M, Ozawa K, Kano Y, Furukawa Y. Kikuchi J, et al. Among authors: izumi t. Blood. 2010 Jul 22;116(3):406-17. doi: 10.1182/blood-2009-07-235663. Epub 2010 Mar 29. Blood. 2010. PMID: 20351311 Free article.

3

The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.

Kikuchi J, Yamada S, Koyama D, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Furukawa Y. Kikuchi J, et al. Among authors: izumi t. J Biol Chem. 2013 Aug 30;288(35):25593-25602. doi: 10.1074/jbc.M113.480574. Epub 2013 Jul 22. J Biol Chem. 2013. PMID: 23878197 Free PMC article. Clinical Trial.

4

Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.

Akutsu M, Furukawa Y, Tsunoda S, Izumi T, Ohmine K, Kano Y. Akutsu M, et al. Among authors: izumi t. Leukemia. 2002 Sep;16(9):1808-17. doi: 10.1038/sj.leu.2402573. Leukemia. 2002. PMID: 12200697

5

The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.

Tanaka M, Kano Y, Akutsu M, Tsunoda S, Izumi T, Yazawa Y, Miyawaki S, Mano H, Furukawa Y. Tanaka M, et al. Among authors: izumi t. Anticancer Res. 2009 Nov;29(11):4589-96. Anticancer Res. 2009. PMID: 20032408 Free article.

6

Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.

Kano Y, Akutsu M, Tsunoda S, Izumi T, Kobayashi H, Mano H, Furukawa Y. Kano Y, et al. Among authors: izumi t. Invest New Drugs. 2007 Feb;25(1):31-40. doi: 10.1007/s10637-006-9000-0. Invest New Drugs. 2007. PMID: 16865529

7

Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

Furukawa Y, Vu HA, Akutsu M, Odgerel T, Izumi T, Tsunoda S, Matsuo Y, Kirito K, Sato Y, Mano H, Kano Y. Furukawa Y, et al. Among authors: izumi t. Leukemia. 2007 May;21(5):1005-14. doi: 10.1038/sj.leu.2404593. Epub 2007 Mar 1. Leukemia. 2007. PMID: 17330105

8

Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide.

Kikuchi J, Kuroda Y, Koyama D, Osada N, Izumi T, Yasui H, Kawase T, Ichinohe T, Furukawa Y. Kikuchi J, et al. Among authors: izumi t. Cancer Res. 2018 Apr 1;78(7):1766-1778. doi: 10.1158/0008-5472.CAN-17-2446. Epub 2018 Jan 23. Cancer Res. 2018. PMID: 29363546

9

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7.

Kikuchi J, Hori M, Iha H, Toyama-Sorimachi N, Hagiwara S, Kuroda Y, Koyama D, Izumi T, Yasui H, Suzuki A, Furukawa Y. Kikuchi J, et al. Among authors: izumi t. Leukemia. 2020 Jan;34(1):180-195. doi: 10.1038/s41375-019-0525-6. Epub 2019 Jul 29. Leukemia. 2020. PMID: 31358854

10

Schedule-dependent synergism and antagonism between pemetrexed and paclitaxel in human carcinoma cell lines in vitro.

Kano Y, Akutsu M, Tsunoda S, Izumi T, Mori K, Fujii H, Yazawa Y, Mano H, Furukawa Y. Kano Y, et al. Among authors: izumi t. Cancer Chemother Pharmacol. 2004 Dec;54(6):505-13. doi: 10.1007/s00280-004-0839-5. Epub 2004 Aug 31. Cancer Chemother Pharmacol. 2004. PMID: 15340759

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