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Use of a bacteriophage lysin to identify a novel target for antimicrobial development.
Schuch R, Pelzek AJ, Raz A, Euler CW, Ryan PA, Winer BY, Farnsworth A, Bhaskaran SS, Stebbins CE, Xu Y, Clifford A, Bearss DJ, Vankayalapati H, Goldberg AR, Fischetti VA. Schuch R, et al. Among authors: bearss dj. PLoS One. 2013 Apr 10;8(4):e60754. doi: 10.1371/journal.pone.0060754. Print 2013. PLoS One. 2013. PMID: 23593301 Free PMC article.
Discovery of Novel Putative Inhibitors of UDP-GlcNAc 2-Epimerase as Potent Antibacterial Agents.
Xu Y, Brenning B, Clifford A, Vollmer D, Bearss J, Jones C, McCarthy V, Shi C, Wolfe B, Aavula B, Warner S, Bearss DJ, McCullar MV, Schuch R, Pelzek A, Bhaskaran SS, Stebbins CE, Goldberg AR, Fischetti VA, Vankayalapati H. Xu Y, et al. Among authors: bearss j, bearss dj. ACS Med Chem Lett. 2013 Dec 12;4(12):1142-1147. doi: 10.1021/ml4001936. ACS Med Chem Lett. 2013. PMID: 24443700 Free PMC article.
Targeting Axl and Mer kinases in cancer.
Verma A, Warner SL, Vankayalapati H, Bearss DJ, Sharma S. Verma A, et al. Among authors: bearss dj. Mol Cancer Ther. 2011 Oct;10(10):1763-73. doi: 10.1158/1535-7163.MCT-11-0116. Epub 2011 Sep 20. Mol Cancer Ther. 2011. PMID: 21933973 Review.
Inhibition of Nek2 by small molecules affects proteasome activity.
Meng L, Carpenter K, Mollard A, Vankayalapati H, Warner SL, Sharma S, Tricot G, Zhan F, Bearss DJ. Meng L, et al. Among authors: bearss dj. Biomed Res Int. 2014;2014:273180. doi: 10.1155/2014/273180. Epub 2014 Sep 17. Biomed Res Int. 2014. PMID: 25313354 Free PMC article.
77 results