Capuano B - Search Results

1

Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.

Jörg M, Shonberg J, Mak FS, Miller ND, Yuriev E, Scammells PJ, Capuano B. Jörg M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3427-33. doi: 10.1016/j.bmcl.2013.03.070. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23602401

2

Homology modeling and docking evaluation of aminergic G protein-coupled receptors.

McRobb FM, Capuano B, Crosby IT, Chalmers DK, Yuriev E. McRobb FM, et al. Among authors: capuano b. J Chem Inf Model. 2010 Apr 26;50(4):626-37. doi: 10.1021/ci900444q. J Chem Inf Model. 2010. PMID: 20187660

3

Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase.

Velkov T, Horne J, Scanlon MJ, Capuano B, Yuriev E, Lawen A. Velkov T, et al. Among authors: capuano b. Chem Biol. 2011 Apr 22;18(4):464-75. doi: 10.1016/j.chembiol.2011.01.017. Chem Biol. 2011. PMID: 21513883

4

Design strategies for bivalent ligands targeting GPCRs.

Shonberg J, Scammells PJ, Capuano B. Shonberg J, et al. Among authors: capuano b. ChemMedChem. 2011 Jun 6;6(6):963-74. doi: 10.1002/cmdc.201100101. Epub 2011 Apr 21. ChemMedChem. 2011. PMID: 21520422 Review.

5

The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors.

Szabo M, Agostino M, Malone DT, Yuriev E, Capuano B. Szabo M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6782-7. doi: 10.1016/j.bmcl.2011.09.038. Epub 2011 Sep 18. Bioorg Med Chem Lett. 2011. PMID: 21982493

6

Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation.

McRobb FM, Crosby IT, Yuriev E, Lane JR, Capuano B. McRobb FM, et al. Among authors: capuano b. J Med Chem. 2012 Feb 23;55(4):1622-34. doi: 10.1021/jm201420s. Epub 2012 Feb 2. J Med Chem. 2012. PMID: 22243698

7

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6-tetrahydropyridines as 5-HT₂C agonists.

Conway RJ, Valant C, Christopoulos A, Robertson AD, Capuano B, Crosby IT. Conway RJ, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2560-4. doi: 10.1016/j.bmcl.2012.01.122. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22381048

8

Synthesis and biological evaluation of N-substituted noscapine analogues.

DeBono AJ, Xie JH, Ventura S, Pouton CW, Capuano B, Scammells PJ. DeBono AJ, et al. Among authors: capuano b. ChemMedChem. 2012 Dec;7(12):2122-33. doi: 10.1002/cmdc.201200365. Epub 2012 Oct 10. ChemMedChem. 2012. PMID: 23055449

9

Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.

Mistry SN, Valant C, Sexton PM, Capuano B, Christopoulos A, Scammells PJ. Mistry SN, et al. Among authors: capuano b. J Med Chem. 2013 Jun 27;56(12):5151-72. doi: 10.1021/jm400540b. Epub 2013 Jun 17. J Med Chem. 2013. PMID: 23718562

10

Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor.

Huynh T, Valant C, Crosby IT, Sexton PM, Christopoulos A, Capuano B. Huynh T, et al. Among authors: capuano b. J Med Chem. 2013 Oct 24;56(20):8196-200. doi: 10.1021/jm401032k. Epub 2013 Oct 11. J Med Chem. 2013. PMID: 24074052

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