Velu SE - Search Results

1

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

Chen D, Wang W, Qin JJ, Wang MH, Murugesan S, Nadkarni DH, Velu SE, Wang H, Zhang R. Chen D, et al. Among authors: velu se. Curr Cancer Drug Targets. 2013 Jul;13(6):651-60. doi: 10.2174/15680096113139990040. Curr Cancer Drug Targets. 2013. PMID: 23607596 Free PMC article.

2

Preclinical evaluation of anticancer efficacy and pharmacological properties of FBA-TPQ, a novel synthetic makaluvamine analog.

Zhang X, Xu H, Zhang X, Voruganti S, Murugesan S, Nadkarni DH, Velu SE, Wang MH, Wang W, Zhang R. Zhang X, et al. Among authors: velu se. Mar Drugs. 2012 May;10(5):1138-1155. doi: 10.3390/md10051138. Epub 2012 May 23. Mar Drugs. 2012. PMID: 22822362 Free PMC article.

3

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes.

Xue B, Wang W, Qin JJ, Nijampatnam B, Murugesan S, Kozlovskaya V, Zhang R, Velu SE, Kharlampieva E. Xue B, et al. Among authors: velu se. Acta Biomater. 2017 Aug;58:386-398. doi: 10.1016/j.actbio.2017.06.004. Epub 2017 Jun 3. Acta Biomater. 2017. PMID: 28583901 Free PMC article.

4

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

Wang W, Rayburn ER, Velu SE, Nadkarni DH, Murugesan S, Zhang R. Wang W, et al. Among authors: velu se. Clin Cancer Res. 2009 May 15;15(10):3511-8. doi: 10.1158/1078-0432.CCR-08-2689. Clin Cancer Res. 2009. PMID: 19451594 Free PMC article.

5

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

Wang W, Rayburn ER, Velu SE, Chen D, Nadkarni DH, Murugesan S, Chen D, Zhang R. Wang W, et al. Among authors: velu se. Breast Cancer Res Treat. 2010 Sep;123(2):321-31. doi: 10.1007/s10549-009-0638-0. Epub 2009 Nov 21. Breast Cancer Res Treat. 2010. PMID: 19936915 Free PMC article.

6

Experimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.

Chen T, Xu Y, Guo H, Liu Y, Hu P, Yang X, Li X, Ge S, Velu SE, Nadkarni DH, Wang W, Zhang R, Wang H. Chen T, et al. Among authors: velu se. PLoS One. 2011;6(6):e20729. doi: 10.1371/journal.pone.0020729. Epub 2011 Jun 6. PLoS One. 2011. PMID: 21673964 Free PMC article.

7

Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats.

Yu JX, Voruganti S, Li DD, Qin JJ, Nag S, Xu S, Velu SE, Wang W, Zhang R. Yu JX, et al. Among authors: velu se. Chin J Nat Med. 2015 Jul;13(7):554-60. doi: 10.1016/S1875-5364(15)30051-0. Chin J Nat Med. 2015. PMID: 26233847 Free PMC article.

8

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy.

Wang W, Qin JJ, Voruganti S, Nijampatnam B, Velu SE, Ruan KH, Hu M, Zhou J, Zhang R. Wang W, et al. Among authors: velu se. Cancer Res. 2018 Oct 1;78(19):5656-5667. doi: 10.1158/0008-5472.CAN-17-3939. Epub 2018 Sep 14. Cancer Res. 2018. PMID: 30217928 Free PMC article.

9

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53.

Wang W, Cheng JW, Qin JJ, Hu B, Li X, Nijampatnam B, Velu SE, Fan J, Yang XR, Zhang R. Wang W, et al. Among authors: velu se. Cancer Lett. 2019 Sep 10;459:156-167. doi: 10.1016/j.canlet.2019.114429. Epub 2019 Jun 7. Cancer Lett. 2019. PMID: 31181320 Free PMC article.

10

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Wang F, Ezell SJ, Zhang Y, Wang W, Rayburn ER, Nadkarni DH, Murugesan S, Velu SE, Zhang R. Wang F, et al. Among authors: velu se. Invest New Drugs. 2010 Jun;28(3):234-41. doi: 10.1007/s10637-009-9232-x. Epub 2009 Mar 10. Invest New Drugs. 2010. PMID: 19274441 Free PMC article.

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