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The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-α production.
Laurent S, Queirolo P, Boero S, Salvi S, Piccioli P, Boccardo S, Minghelli S, Morabito A, Fontana V, Pietra G, Carrega P, Ferrari N, Tosetti F, Chang LJ, Mingari MC, Ferlazzo G, Poggi A, Pistillo MP. Laurent S, et al. Among authors: pistillo mp. J Transl Med. 2013 May 1;11:108. doi: 10.1186/1479-5876-11-108. J Transl Med. 2013. PMID: 23634660 Free PMC article.
Investigation of HLA class I downregulation in breast cancer by RT-PCR.
Palmisano GL, Pistillo MP, Capanni P, Pera C, Nicolò G, Salvi S, Perdelli L, Pasciucco G, Ferrara GB. Palmisano GL, et al. Among authors: pistillo mp. Hum Immunol. 2001 Feb;62(2):133-9. doi: 10.1016/s0198-8859(00)00241-x. Hum Immunol. 2001. PMID: 11182222
Analysis of HLA-G expression in breast cancer tissues.
Palmisano GL, Pistillo MP, Fardin P, Capanni P, Nicolò G, Salvi S, Spina B, Pasciucco G, Ferrara GB. Palmisano GL, et al. Among authors: pistillo mp. Hum Immunol. 2002 Nov;63(11):969-76. doi: 10.1016/s0198-8859(02)00642-0. Hum Immunol. 2002. PMID: 12392849
CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.
Pistillo MP, Tazzari PL, Palmisano GL, Pierri I, Bolognesi A, Ferlito F, Capanni P, Polito L, Ratta M, Pileri S, Piccioli M, Basso G, Rissotto L, Conte R, Gobbi M, Stirpe F, Ferrara GB. Pistillo MP, et al. Blood. 2003 Jan 1;101(1):202-9. doi: 10.1182/blood-2002-06-1668. Epub 2002 Aug 15. Blood. 2003. PMID: 12393538 Free article.
CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
Laurent S, Palmisano GL, Martelli AM, Kato T, Tazzari PL, Pierri I, Clavio M, Dozin B, Balbi G, Megna M, Morabito A, Lamparelli T, Bacigalupo A, Gobbi M, Pistillo MP. Laurent S, et al. Among authors: pistillo mp. Br J Haematol. 2007 Feb;136(4):597-608. doi: 10.1111/j.1365-2141.2006.06472.x. Br J Haematol. 2007. PMID: 17367412 Free article.
Association of -318 C/T and +49 A/G cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms with a clinical subset of Italian patients with systemic sclerosis.
Balbi G, Ferrera F, Rizzi M, Piccioli P, Morabito A, Cardamone L, Ghio M, Palmisano GL, Carrara P, Pedemonte S, Sessarego M, De Angioletti M, Notaro R, Indiveri F, Pistillo MP. Balbi G, et al. Among authors: pistillo mp. Clin Exp Immunol. 2007 Jul;149(1):40-7. doi: 10.1111/j.1365-2249.2007.03394.x. Epub 2007 Apr 25. Clin Exp Immunol. 2007. PMID: 17459075 Free PMC article.
CTLA-4 +49A>G polymorphism of recipients of HLA-matched sibling allogeneic stem cell transplantation is associated with survival and relapse incidence.
Piccioli P, Balbi G, Serra M, Morabito A, Lamparelli T, Gobbi M, Laurent S, Dozin B, Bruzzi P, Ferraris AM, Bacigalupo A, Notaro R, Pistillo MP. Piccioli P, et al. Among authors: pistillo mp. Ann Hematol. 2010 Jun;89(6):613-8. doi: 10.1007/s00277-009-0885-5. Epub 2009 Dec 18. Ann Hematol. 2010. PMID: 20020126
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