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Practical and innate carbon-hydrogen functionalization of heterocycles.
Fujiwara Y, Dixon JA, O'Hara F, Funder ED, Dixon DD, Rodriguez RA, Baxter RD, Herlé B, Sach N, Collins MR, Ishihara Y, Baran PS. Fujiwara Y, et al. Nature. 2012 Dec 6;492(7427):95-9. doi: 10.1038/nature11680. Epub 2012 Nov 28. Nature. 2012. PMID: 23201691 Free PMC article.
Innate C-H trifluoromethylation of heterocycles.
Ji Y, Brueckl T, Baxter RD, Fujiwara Y, Seiple IB, Su S, Blackmond DG, Baran PS. Ji Y, et al. Among authors: fujiwara y. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14411-5. doi: 10.1073/pnas.1109059108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844378 Free PMC article.
A new reagent for direct difluoromethylation.
Fujiwara Y, Dixon JA, Rodriguez RA, Baxter RD, Dixon DD, Collins MR, Blackmond DG, Baran PS. Fujiwara Y, et al. J Am Chem Soc. 2012 Jan 25;134(3):1494-7. doi: 10.1021/ja211422g. Epub 2012 Jan 13. J Am Chem Soc. 2012. PMID: 22229949 Free PMC article.
A simple litmus test for aldehyde oxidase metabolism of heteroarenes.
O'Hara F, Burns AC, Collins MR, Dalvie D, Ornelas MA, Vaz AD, Fujiwara Y, Baran PS. O'Hara F, et al. Among authors: fujiwara y. J Med Chem. 2014 Feb 27;57(4):1616-20. doi: 10.1021/jm4017976. Epub 2014 Feb 5. J Med Chem. 2014. PMID: 24472070 Free PMC article.
Practical C-H functionalization of quinones with boronic acids.
Fujiwara Y, Domingo V, Seiple IB, Gianatassio R, Del Bel M, Baran PS. Fujiwara Y, et al. J Am Chem Soc. 2011 Mar 16;133(10):3292-5. doi: 10.1021/ja111152z. Epub 2011 Feb 22. J Am Chem Soc. 2011. PMID: 21341741 Free PMC article.
Direct synthesis of fluorinated heteroarylether bioisosteres.
Zhou Q, Ruffoni A, Gianatassio R, Fujiwara Y, Sella E, Shabat D, Baran PS. Zhou Q, et al. Among authors: fujiwara y. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3949-52. doi: 10.1002/anie.201300763. Epub 2013 Mar 4. Angew Chem Int Ed Engl. 2013. PMID: 23460402 Free PMC article.
4,270 results