Bort R - Search Results

1

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

Blazquez M, Carretero A, Ellis JK, Athersuch TJ, Cavill R, Ebbels TM, Keun HC, Castell JV, Lahoz A, Bort R. Blazquez M, et al. Among authors: bort r. J Proteome Res. 2013 Jun 7;12(6):2732-41. doi: 10.1021/pr400085n. Epub 2013 May 15. J Proteome Res. 2013. PMID: 23641669

2

Metabolism of aceclofenac in humans.

Bort R, Ponsoda X, Carrasco E, Gómez-Lechón MJ, Castell JV. Bort R, et al. Drug Metab Dispos. 1996 Aug;24(8):834-41. Drug Metab Dispos. 1996. PMID: 8869816

3

Comparative metabolism of the nonsteroidal antiinflammatory drug, aceclofenac, in the rat, monkey, and human.

Bort R, Ponsoda X, Carrasco E, Gómez-Lechón MJ, Castell JV. Bort R, et al. Drug Metab Dispos. 1996 Sep;24(9):969-75. Drug Metab Dispos. 1996. PMID: 8886606

4

In vitro investigation of the molecular mechanisms of hepatotoxicity.

Castell JV, Gómez-Lechón MJ, Ponsoda X, Bort R. Castell JV, et al. Among authors: bort r. Arch Toxicol Suppl. 1997;19:313-21. doi: 10.1007/978-3-642-60682-3_29. Arch Toxicol Suppl. 1997. PMID: 9079218 Review. No abstract available.

5

The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity.

Castell JV, Gómez-Lechón MJ, Ponsoda X, Bort R. Castell JV, et al. Among authors: bort r. Cell Biol Toxicol. 1997 Jul;13(4-5):331-8. doi: 10.1023/a:1007443610025. Cell Biol Toxicol. 1997. PMID: 9298253 Review.

6

Re-expression of C/EBP alpha induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells.

Jover R, Bort R, Gómez-Lechón MJ, Castell JV. Jover R, et al. Among authors: bort r. FEBS Lett. 1998 Jul 17;431(2):227-30. doi: 10.1016/s0014-5793(98)00746-7. FEBS Lett. 1998. PMID: 9708908 Free article.

7

Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity.

Bort R, Ponsoda X, Jover R, Gómez-Lechón MJ, Castell JV. Bort R, et al. J Pharmacol Exp Ther. 1999 Jan;288(1):65-72. J Pharmacol Exp Ther. 1999. PMID: 9862754

8

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix.

Gómez-Lechón MJ, Jover R, Donato T, Ponsoda X, Rodriguez C, Stenzel KG, Klocke R, Paul D, Guillén I, Bort R, Castell JV. Gómez-Lechón MJ, et al. Among authors: bort r. J Cell Physiol. 1998 Dec;177(4):553-62. doi: 10.1002/(SICI)1097-4652(199812)177:4<553::AID-JCP6>3.0.CO;2-F. J Cell Physiol. 1998. PMID: 10092208

9

Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways.

Bort R, Macé K, Boobis A, Gómez-Lechón MJ, Pfeifer A, Castell J. Bort R, et al. Biochem Pharmacol. 1999 Sep 1;58(5):787-96. doi: 10.1016/s0006-2952(99)00167-7. Biochem Pharmacol. 1999. PMID: 10449188

10

Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH.

Ponsoda X, Bort R, Jover R, Gómez-Lechón MJ, Castell JV. Ponsoda X, et al. Among authors: bort r. Biochem Pharmacol. 1999 Nov 15;58(10):1579-85. doi: 10.1016/s0006-2952(99)00249-x. Biochem Pharmacol. 1999. PMID: 10535748

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