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Page 1
Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A.
DeGoey DA, Betebenner DA, Grampovnik DJ, Liu D, Pratt JK, Tufano MD, He W, Krishnan P, Pilot-Matias TJ, Marsh KC, Molla A, Kempf DJ, Maring CJ. DeGoey DA, et al. Among authors: grampovnik dj. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3627-30. doi: 10.1016/j.bmcl.2013.04.009. Epub 2013 Apr 10. Bioorg Med Chem Lett. 2013. PMID: 23642966
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
Degoey DA, Grampovnik DJ, Flentge CA, Flosi WJ, Chen HJ, Yeung CM, Randolph JT, Klein LL, Dekhtyar T, Colletti L, Marsh KC, Stoll V, Mamo M, Morfitt DC, Nguyen B, Schmidt JM, Swanson SJ, Mo H, Kati WM, Molla A, Kempf DJ. Degoey DA, et al. Among authors: grampovnik dj. J Med Chem. 2009 Apr 23;52(8):2571-86. doi: 10.1021/jm900044w. J Med Chem. 2009. PMID: 19323562
Enantioselective synthesis of antiinfluenza compound A-315675.
DeGoey DA, Chen HJ, Flosi WJ, Grampovnik DJ, Yeung CM, Klein LL, Kempf DJ. DeGoey DA, et al. Among authors: grampovnik dj. J Org Chem. 2002 Aug 9;67(16):5445-53. doi: 10.1021/jo0162890. J Org Chem. 2002. PMID: 12153241
Total synthesis and antifungal evaluation of cyclic aminohexapeptides.
Klein LL, Li L, Chen HJ, Curty CB, DeGoey DA, Grampovnik DJ, Leone CL, Thomas SA, Yeung CM, Funk KW, Kishore V, Lundell EO, Wodka D, Meulbroek JA, Alder JD, Nilius AM, Lartey PA, Plattner JJ. Klein LL, et al. Among authors: grampovnik dj. Bioorg Med Chem. 2000 Jul;8(7):1677-96. doi: 10.1016/s0968-0896(00)00097-3. Bioorg Med Chem. 2000. PMID: 10976515
Antitumor activity of 9(R)-dihydrotaxane analogs.
Klein LL, Li L, Maring CJ, Yeung CM, Thomas SA, Grampovnik DJ, Plattner JJ. Klein LL, et al. Among authors: grampovnik dj. J Med Chem. 1995 Apr 28;38(9):1482-92. doi: 10.1021/jm00009a009. J Med Chem. 1995. PMID: 7739007
15 results