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A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.
Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. Piazza GA, et al. Among authors: mathew b. Cancer Prev Res (Phila). 2009 Jun;2(6):572-80. doi: 10.1158/1940-6207.CAPR-09-0001. Epub 2009 May 26. Cancer Prev Res (Phila). 2009. PMID: 19470791 Free PMC article.
Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.
Mathew B, Srivastava S, Ross LJ, Suling WJ, White EL, Woolhiser LK, Lenaerts AJ, Reynolds RC. Mathew B, et al. Bioorg Med Chem. 2011 Dec 1;19(23):7120-8. doi: 10.1016/j.bmc.2011.09.062. Epub 2011 Oct 5. Bioorg Med Chem. 2011. PMID: 22024272 Free PMC article.
NSAIDs: Old Drugs Reveal New Anticancer Targets.
Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary BD, Mathew B, Singh R, Grizzle WE, Reynolds RC. Piazza GA, et al. Among authors: mathew b. Pharmaceuticals (Basel). 2010 May 25;3(5):1652-1667. doi: 10.3390/ph3051652. Pharmaceuticals (Basel). 2010. PMID: 27713322 Free PMC article. Review.
Amine Containing Analogs of Sulindac for Cancer Prevention.
Mathew B, Hobrath JV, Connelly MC, Guy RK, Reynolds RC. Mathew B, et al. Open Med Chem J. 2018 Jan 31;12:1-12. doi: 10.2174/1874104501812010001. eCollection 2018. Open Med Chem J. 2018. PMID: 29492166 Free PMC article.
Oxazole and thiazole analogs of sulindac for cancer prevention.
Mathew B, Hobrath JV, Connelly MC, Guy RK, Reynolds RC. Mathew B, et al. Future Med Chem. 2018 Apr 1;10(7):743-753. doi: 10.4155/fmc-2017-0182. Epub 2018 Apr 19. Future Med Chem. 2018. PMID: 29671617 Free PMC article.
799 results