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Page 1
MicroRNAs as potential therapeutic targets in kidney disease.
Gomez IG, Grafals M, Portilla D, Duffield JS. Gomez IG, et al. Among authors: portilla d. J Formos Med Assoc. 2013 May;112(5):237-43. doi: 10.1016/j.jfma.2012.12.011. Epub 2013 Feb 4. J Formos Med Assoc. 2013. PMID: 23660218 Free PMC article. Review.
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Chau BN, Xin C, Hartner J, Ren S, Castano AP, Linn G, Li J, Tran PT, Kaimal V, Huang X, Chang AN, Li S, Kalra A, Grafals M, Portilla D, MacKenna DA, Orkin SH, Duffield JS. Chau BN, et al. Among authors: portilla d. Sci Transl Med. 2012 Feb 15;4(121):121ra18. doi: 10.1126/scitranslmed.3003205. Sci Transl Med. 2012. PMID: 22344686 Free PMC article.
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS. Gomez IG, et al. Among authors: portilla d. J Clin Invest. 2015 Jan;125(1):141-56. doi: 10.1172/JCI75852. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415439 Free PMC article.
Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.
Xavier S, Sahu RK, Landes SG, Yu J, Taylor RP, Ayyadevara S, Megyesi J, Stallcup WB, Duffield JS, Reis ES, Lambris JD, Portilla D. Xavier S, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F516-F532. doi: 10.1152/ajprenal.00604.2016. Epub 2017 Jan 4. Am J Physiol Renal Physiol. 2017. PMID: 28052876 Free PMC article.
Apoptosis, fibrosis and senescence.
Portilla D. Portilla D. Nephron Clin Pract. 2014;127(1-4):65-9. doi: 10.1159/000363717. Epub 2014 Sep 24. Nephron Clin Pract. 2014. PMID: 25343824 Review.
Targeting Endogenous Repair Pathways after AKI.
Humphreys BD, Cantaluppi V, Portilla D, Singbartl K, Yang L, Rosner MH, Kellum JA, Ronco C; Acute Dialysis Quality Initiative (ADQI) XIII Work Group. Humphreys BD, et al. Among authors: portilla d. J Am Soc Nephrol. 2016 Apr;27(4):990-8. doi: 10.1681/ASN.2015030286. Epub 2015 Nov 18. J Am Soc Nephrol. 2016. PMID: 26582401 Free PMC article. Review.
Complement C1r serine protease contributes to kidney fibrosis.
Xavier S, Sahu RK, Bontha SV, Mass V, Taylor RP, Megyesi J, Thielens NM, Portilla D. Xavier S, et al. Among authors: portilla d. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1293-F1304. doi: 10.1152/ajprenal.00357.2019. Epub 2019 Sep 11. Am J Physiol Renal Physiol. 2019. PMID: 31509012 Free PMC article.
78 results