Bowlin TL - Search Results

1

Optimization of a novel potent and selective bacterial DNA helicase inhibitor scaffold from a high throughput screening hit.

Li B, Pai R, Aiello D, Di M, Barnes MH, Peet NP, Bowlin TL, Moir DT. Li B, et al. Among authors: bowlin tl. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3481-6. doi: 10.1016/j.bmcl.2013.04.055. Epub 2013 Apr 30. Bioorg Med Chem Lett. 2013. PMID: 23664213 Free PMC article.

2

Carbocyclic nucleosides as inhibitors of human tumor necrosis factor-alpha production: effects of the stereoisomers of (3-hydroxycyclopentyl)adenines.

Borcherding DR, Peet NP, Munson HR, Zhang H, Hoffman PF, Bowlin TL, Edwards CK 3rd. Borcherding DR, et al. Among authors: bowlin tl. J Med Chem. 1996 Jun 21;39(13):2615-20. doi: 10.1021/jm950906t. J Med Chem. 1996. PMID: 8691460

3

Antibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound.

Butler MM, Lamarr WA, Foster KA, Barnes MH, Skow DJ, Lyden PT, Kustigian LM, Zhi C, Brown NC, Wright GE, Bowlin TL. Butler MM, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2007 Jan;51(1):119-27. doi: 10.1128/AAC.01311-05. Epub 2006 Oct 30. Antimicrob Agents Chemother. 2007. PMID: 17074800 Free PMC article.

4

A high-throughput, homogeneous, bioluminescent assay for Pseudomonas aeruginosa gyrase inhibitors and other DNA-damaging agents.

Moir DT, Ming Di, Opperman T, Schweizer HP, Bowlin TL. Moir DT, et al. Among authors: bowlin tl. J Biomol Screen. 2007 Sep;12(6):855-64. doi: 10.1177/1087057107304729. Epub 2007 Jul 20. J Biomol Screen. 2007. PMID: 17644773 Free PMC article.

5

Discovery, characterization and comparison of inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicases.

Aiello D, Barnes MH, Biswas EE, Biswas SB, Gu S, Williams JD, Bowlin TL, Moir DT. Aiello D, et al. Among authors: bowlin tl. Bioorg Med Chem. 2009 Jul 1;17(13):4466-76. doi: 10.1016/j.bmc.2009.05.014. Epub 2009 May 12. Bioorg Med Chem. 2009. PMID: 19477652 Free PMC article.

6

Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activities against antibiotic-resistant strains.

Panchal RG, Ulrich RL, Lane D, Butler MM, Houseweart C, Opperman T, Williams JD, Peet NP, Moir DT, Nguyen T, Gussio R, Bowlin T, Bavari S. Panchal RG, et al. Antimicrob Agents Chemother. 2009 Oct;53(10):4283-91. doi: 10.1128/AAC.01709-08. Epub 2009 Jul 27. Antimicrob Agents Chemother. 2009. PMID: 19635954 Free PMC article.

7

Aryl rhodanines specifically inhibit staphylococcal and enterococcal biofilm formation.

Opperman TJ, Kwasny SM, Williams JD, Khan AR, Peet NP, Moir DT, Bowlin TL. Opperman TJ, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2009 Oct;53(10):4357-67. doi: 10.1128/AAC.00077-09. Epub 2009 Aug 3. Antimicrob Agents Chemother. 2009. PMID: 19651903 Free PMC article.

8

Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors.

Li B, Pai R, Cardinale SC, Butler MM, Peet NP, Moir DT, Bavari S, Bowlin TL. Li B, et al. Among authors: bowlin tl. J Med Chem. 2010 Mar 11;53(5):2264-76. doi: 10.1021/jm901852f. J Med Chem. 2010. PMID: 20155918 Free PMC article.

9

Discovery and characterization of inhibitors of Pseudomonas aeruginosa type III secretion.

Aiello D, Williams JD, Majgier-Baranowska H, Patel I, Peet NP, Huang J, Lory S, Bowlin TL, Moir DT. Aiello D, et al. Among authors: bowlin tl. Antimicrob Agents Chemother. 2010 May;54(5):1988-99. doi: 10.1128/AAC.01598-09. Epub 2010 Feb 22. Antimicrob Agents Chemother. 2010. PMID: 20176902 Free PMC article.

10

Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.

Opperman TJ, Williams JD, Houseweart C, Panchal RG, Bavari S, Peet NP, Moir DT, Bowlin TL. Opperman TJ, et al. Among authors: bowlin tl. Bioorg Med Chem. 2010 Mar 15;18(6):2123-2130. doi: 10.1016/j.bmc.2010.02.005. Epub 2010 Feb 10. Bioorg Med Chem. 2010. PMID: 20188576

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