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Precision Activity-Based α-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes.
Pickles IB, Chen Y, Moroz O, Brown HA, de Boer C, Armstrong Z, McGregor NGS, Artola M, Codée JDC, Koropatkin NM, Overkleeft HS, Davies GJ. Pickles IB, et al. Among authors: davies gj. Angew Chem Int Ed Engl. 2024 Nov 27:e202415219. doi: 10.1002/anie.202415219. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39601378
Development of Tunable Mechanism-Based Carbasugar Ligands that Stabilize Glycoside Hydrolases through the Formation of Transient Covalent Intermediates.
Bhosale S, Kandalkar S, Gilormini PA, Akintola O, Rowland R, Adabala PJP, King D, Deen MC, Chen X, Davies GJ, Vocadlo DJ, Bennet AJ. Bhosale S, et al. Among authors: davies gj. ACS Catal. 2024 Sep 20;14(19):14769-14779. doi: 10.1021/acscatal.4c04549. eCollection 2024 Oct 4. ACS Catal. 2024. PMID: 39386917 Free PMC article.
A Bioorthogonal Precision Tool for Human N-Acetylglucosaminyltransferase V.
Liu Y, Bineva-Todd G, Meek RW, Mazo L, Piniello B, Moroz O, Burnap SA, Begum N, Ohara A, Roustan C, Tomita S, Kjaer S, Polizzi K, Struwe WB, Rovira C, Davies GJ, Schumann B. Liu Y, et al. Among authors: davies gj. J Am Chem Soc. 2024 Oct 2;146(39):26707-26718. doi: 10.1021/jacs.4c05955. Epub 2024 Sep 17. J Am Chem Soc. 2024. PMID: 39287665 Free PMC article.
Epi-Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α-Glucosidase II Inhibitor, Blocks Replication of SARS-CoV-2 and Other Coronaviruses.
Thaler M, Ofman TP, Kok K, Heming JJA, Moran E, Pickles I, Leijs AA, van den Nieuwendijk AMCH, van den Berg RJBHN, Ruijgrok G, Armstrong Z, Salgado-Benvindo C, Ninaber DK, Snijder EJ, van Boeckel CAA, Artola M, Davies GJ, Overkleeft HS, van Hemert MJ. Thaler M, et al. Among authors: davies gj. ACS Cent Sci. 2024 Jul 25;10(8):1594-1608. doi: 10.1021/acscentsci.4c00506. eCollection 2024 Aug 28. ACS Cent Sci. 2024. PMID: 39220688 Free PMC article.
623 results