Hackett JA - Search Results

1

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation.

Grabole N, Tischler J, Hackett JA, Kim S, Tang F, Leitch HG, Magnúsdóttir E, Surani MA. Grabole N, et al. Among authors: hackett ja. EMBO Rep. 2013 Jul;14(7):629-37. doi: 10.1038/embor.2013.67. Epub 2013 May 14. EMBO Rep. 2013. PMID: 23670199 Free PMC article.

2

DNA methylation dynamics during the mammalian life cycle.

Hackett JA, Surani MA. Hackett JA, et al. Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20110328. doi: 10.1098/rstb.2011.0328. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23166392 Free PMC article. Review.

3

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

Hackett JA, Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA. Hackett JA, et al. Science. 2013 Jan 25;339(6118):448-52. doi: 10.1126/science.1229277. Epub 2012 Dec 6. Science. 2013. PMID: 23223451 Free PMC article.

4

Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency.

Hackett JA, Dietmann S, Murakami K, Down TA, Leitch HG, Surani MA. Hackett JA, et al. Stem Cell Reports. 2013 Dec 17;1(6):518-31. doi: 10.1016/j.stemcr.2013.11.010. eCollection 2013. Stem Cell Reports. 2013. PMID: 24371807 Free PMC article.

5

Dynamic heterogeneity and DNA methylation in embryonic stem cells.

Singer ZS, Yong J, Tischler J, Hackett JA, Altinok A, Surani MA, Cai L, Elowitz MB. Singer ZS, et al. Among authors: hackett ja. Mol Cell. 2014 Jul 17;55(2):319-31. doi: 10.1016/j.molcel.2014.06.029. Mol Cell. 2014. PMID: 25038413 Free PMC article.

6

Regulatory principles of pluripotency: from the ground state up.

Hackett JA, Surani MA. Hackett JA, et al. Cell Stem Cell. 2014 Oct 2;15(4):416-430. doi: 10.1016/j.stem.2014.09.015. Cell Stem Cell. 2014. PMID: 25280218 Free article. Review.

7

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development.

Tang WW, Dietmann S, Irie N, Leitch HG, Floros VI, Bradshaw CR, Hackett JA, Chinnery PF, Surani MA. Tang WW, et al. Among authors: hackett ja. Cell. 2015 Jun 4;161(6):1453-67. doi: 10.1016/j.cell.2015.04.053. Cell. 2015. PMID: 26046444 Free PMC article.

8

Tracing the transitions from pluripotency to germ cell fate with CRISPR screening.

Hackett JA, Huang Y, Günesdogan U, Gretarsson KA, Kobayashi T, Surani MA. Hackett JA, et al. Nat Commun. 2018 Oct 16;9(1):4292. doi: 10.1038/s41467-018-06230-0. Nat Commun. 2018. PMID: 30327475 Free PMC article.

9

Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum.

Hackett JA, Kobayashi T, Dietmann S, Surani MA. Hackett JA, et al. Stem Cell Reports. 2017 Jun 6;8(6):1645-1658. doi: 10.1016/j.stemcr.2017.05.014. Stem Cell Reports. 2017. PMID: 28591649 Free PMC article.

10

Parallel mechanisms of epigenetic reprogramming in the germline.

Hackett JA, Zylicz JJ, Surani MA. Hackett JA, et al. Trends Genet. 2012 Apr;28(4):164-74. doi: 10.1016/j.tig.2012.01.005. Epub 2012 Mar 3. Trends Genet. 2012. PMID: 22386917 Review.

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