O'Connor DT - Search Results

1

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension.

Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork NJ, Pravenec M, Mahata SK, Schmid-Schönbein GW, O'Connor DT. Friese RS, et al. Hum Mol Genet. 2013 Sep 15;22(18):3624-40. doi: 10.1093/hmg/ddt213. Epub 2013 May 13. Hum Mol Genet. 2013. PMID: 23674521 Free PMC article.

2

The angiotensin II receptor (Agtr1a): functional regulatory polymorphisms in a locus genetically linked to blood pressure variation in the mouse.

Wong C, Mahapatra NR, Chitbangonsyn S, Mahboubi P, Mahata M, Mahata SK, O'Connor DT. Wong C, et al. Physiol Genomics. 2003 Jun 24;14(1):83-93. doi: 10.1152/physiolgenomics.00162.2002. Physiol Genomics. 2003. PMID: 12697907

3

Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.

Wen G, Mahata SK, Cadman P, Mahata M, Ghosh S, Mahapatra NR, Rao F, Stridsberg M, Smith DW, Mahboubi P, Schork NJ, O'Connor DT, Hamilton BA. Wen G, et al. Am J Hum Genet. 2004 Feb;74(2):197-207. doi: 10.1086/381399. Epub 2004 Jan 12. Am J Hum Genet. 2004. PMID: 14740315 Free PMC article.

4

Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension.

Friese RS, Mahboubi P, Mahapatra NR, Mahata SK, Schork NJ, Schmid-Schönbein GW, O'Connor DT. Friese RS, et al. Am J Hypertens. 2005 May;18(5 Pt 1):633-52. doi: 10.1016/j.amjhyper.2004.11.037. Am J Hypertens. 2005. PMID: 15882546

5

An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension.

Wen G, Wessel J, Zhou W, Ehret GB, Rao F, Stridsberg M, Mahata SK, Gent PM, Das M, Cooper RS, Chakravarti A, Zhou H, Schork NJ, O'connor DT, Hamilton BA. Wen G, et al. Hum Mol Genet. 2007 Jul 15;16(14):1752-64. doi: 10.1093/hmg/ddm123. Epub 2007 Jun 21. Hum Mol Genet. 2007. PMID: 17584765 Free PMC article.

6

Global metabolic consequences of the chromogranin A-null model of hypertension: transcriptomic detection, pathway identification, and experimental verification.

Friese RS, Gayen JR, Mahapatra NR, Schmid-Schönbein GW, O'Connor DT, Mahata SK. Friese RS, et al. Physiol Genomics. 2010 Feb 4;40(3):195-207. doi: 10.1152/physiolgenomics.00164.2009. Epub 2009 Dec 1. Physiol Genomics. 2010. PMID: 19952279 Free PMC article.

7

Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.

Vaingankar SM, Li Y, Corti A, Biswas N, Gayen J, O'Connor DT, Mahata SK. Vaingankar SM, et al. Physiol Genomics. 2010 Mar 3;41(1):91-101. doi: 10.1152/physiolgenomics.00086.2009. Epub 2009 Dec 15. Physiol Genomics. 2010. PMID: 20009010 Free PMC article.

8

Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses.

Vaingankar SM, Li Y, Biswas N, Gayen J, Choksi S, Rao F, Ziegler MG, Mahata SK, O'Connor DT. Vaingankar SM, et al. J Hypertens. 2010 Apr;28(4):817-25. doi: 10.1097/HJH.0b013e328336ed3e. J Hypertens. 2010. PMID: 20139771 Free PMC article.

9

Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension.

Zhang K, Rao F, Wang L, Rana BK, Ghosh S, Mahata M, Salem RM, Rodriguez-Flores JL, Fung MM, Waalen J, Tayo B, Taupenot L, Mahata SK, O'Connor DT. Zhang K, et al. J Am Coll Cardiol. 2010 Apr 6;55(14):1463-75. doi: 10.1016/j.jacc.2009.11.064. J Am Coll Cardiol. 2010. PMID: 20359597 Free PMC article.

10

Role of reactive oxygen species in hyperadrenergic hypertension: biochemical, physiological, and pharmacological evidence from targeted ablation of the chromogranin a (Chga) gene.

Gayen JR, Zhang K, RamachandraRao SP, Mahata M, Chen Y, Kim HS, Naviaux RK, Sharma K, Mahata SK, O'Connor DT. Gayen JR, et al. Circ Cardiovasc Genet. 2010 Oct;3(5):414-25. doi: 10.1161/CIRCGENETICS.109.924050. Epub 2010 Aug 20. Circ Cardiovasc Genet. 2010. PMID: 20729505 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

419 results

Search Page

Filters